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Structure-based optimization of aminopyridines as PKCθ inhibitors.
Jimenez JM, Davis C, Boyall D, Fraysse D, Knegtel R, Settimo L, Young S, Bolton C, Chiu P, Curnock A, Rasmussen R, Tanner A, Ager I. Jimenez JM, et al. Among authors: bolton c. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4645-9. doi: 10.1016/j.bmcl.2012.05.114. Epub 2012 Jun 6. Bioorg Med Chem Lett. 2012. PMID: 22738630
Design and optimization of selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases.
Jimenez JM, Boyall D, Brenchley G, Collier PN, Davis CJ, Fraysse D, Keily SB, Henderson J, Miller A, Pierard F, Settimo L, Twin HC, Bolton CM, Curnock AP, Chiu P, Tanner AJ, Young S. Jimenez JM, et al. Among authors: bolton cm. J Med Chem. 2013 Mar 14;56(5):1799-810. doi: 10.1021/jm301465a. Epub 2013 Feb 11. J Med Chem. 2013. PMID: 23398373
Cardiovascular Involvement in Tuberculosis Patients Treated in Southern Africa.
Samim D, Muula G, Banholzer N, Chibomba D, Xulu S, Bolton C, Evans D, Perrig L, De Marchi S, Günther G, Egger M, Pilgrim T, Fenner L; IeDEA Southern Africa (IeDEA-SA). Samim D, et al. Among authors: bolton c. JACC Adv. 2024 Dec 5;4(1):101427. doi: 10.1016/j.jacadv.2024.101427. eCollection 2025 Jan. JACC Adv. 2024. PMID: 39720579 Free PMC article.
Clinical and demographic factors modify the association between plasma phosphorylated tau-181 and cognition.
Bolton CJ, Steinbach M, Khan OA, Liu D, O'Malley J, Dumitrescu L, Peterson A, Jefferson AL, Hohman TJ, Zetterberg H, Gifford KA; Alzheimer's Disease Neuroimaging Initiative. Bolton CJ, et al. Alzheimers Dement (Amst). 2024 Dec 20;16(4):e70047. doi: 10.1002/dad2.70047. eCollection 2024 Oct-Dec. Alzheimers Dement (Amst). 2024. PMID: 39713247 Free PMC article.
Incidence of diabetes mellitus following hospitalisation for COVID-19 in the United Kingdom: A prospective observational study.
Tyrer F, Gharibzadeh S, Gillies C, Lawson C, Routen A, Islam N, Razieh C, Zaccardi F, Yates T, Davies MJ, Brightling CE, Chalmers JD, Docherty AB, Elneima O, Evans RA, Greening NJ, Harris VC, Harrison EM, Ho LP, Horsley A, Houchen-Wolloff L, Leavy OC, Lone NI, Marks M, McAuley HJC, Poinasamy K, Quint JK, Raman B, Richardson M, Saunders R, Sereno M, Shikotra A, Singapuri A, Wain LV, Khunti K; PHOSP‐COVID Study Collaborative Group. Tyrer F, et al. Diabetes Obes Metab. 2025 Feb;27(2):767-776. doi: 10.1111/dom.16071. Epub 2024 Nov 20. Diabetes Obes Metab. 2025. PMID: 39563623 Free PMC article.
Nepal Family Cohort study: a study protocol.
Kurmi OP, Chaudhary N, Delanerolle G, Bolton CE, Pant PR, Regmi PR, Gautam S, Satia I, Simkhada P, Kyrou I, Sigdel TK, Hundley V, Dali PR, Løkke A, Lam KBH, Bennett D, Custovic A, van Teijlingen E, Gill P, Randeva H, O'Byrne P; Nepal Family Cohort Collaborators. Kurmi OP, et al. Among authors: bolton ce. BMJ Open. 2024 Nov 9;14(11):e088896. doi: 10.1136/bmjopen-2024-088896. BMJ Open. 2024. PMID: 39521464 Free PMC article.
550 results