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Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells.
Zhang Y, Yan X, Sashida G, Zhao X, Rao Y, Goyama S, Whitman SP, Zorko N, Bernot K, Conway RM, Witte D, Wang QF, Tenen DG, Xiao Z, Marcucci G, Mulloy JC, Grimes HL, Caligiuri MA, Huang G. Zhang Y, et al. Among authors: grimes hl. Blood. 2012 Aug 2;120(5):1118-29. doi: 10.1182/blood-2012-02-412379. Epub 2012 Jun 26. Blood. 2012. PMID: 22740449 Free PMC article.
Gfi1 regulates miR-21 and miR-196b to control myelopoiesis.
Velu CS, Baktula AM, Grimes HL. Velu CS, et al. Among authors: grimes hl. Blood. 2009 May 7;113(19):4720-8. doi: 10.1182/blood-2008-11-190215. Epub 2009 Mar 10. Blood. 2009. PMID: 19278956 Free PMC article.
MicroRNAs in the midst of myeloid signal transduction.
Stoffers SL, Meyer SE, Grimes HL. Stoffers SL, et al. Among authors: grimes hl. J Cell Physiol. 2012 Feb;227(2):525-33. doi: 10.1002/jcp.22823. J Cell Physiol. 2012. PMID: 21567394 Free PMC article. Review.
Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress.
Unnisa Z, Clark JP, Roychoudhury J, Thomas E, Tessarollo L, Copeland NG, Jenkins NA, Grimes HL, Kumar AR. Unnisa Z, et al. Among authors: grimes hl. Blood. 2012 Dec 13;120(25):4973-81. doi: 10.1182/blood-2012-06-435800. Epub 2012 Oct 22. Blood. 2012. PMID: 23091297 Free PMC article.
Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells.
Goyama S, Schibler J, Cunningham L, Zhang Y, Rao Y, Nishimoto N, Nakagawa M, Olsson A, Wunderlich M, Link KA, Mizukawa B, Grimes HL, Kurokawa M, Liu PP, Huang G, Mulloy JC. Goyama S, et al. Among authors: grimes hl. J Clin Invest. 2013 Sep;123(9):3876-88. doi: 10.1172/JCI68557. Epub 2013 Aug 27. J Clin Invest. 2013. PMID: 23979164 Free PMC article.
Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity.
Velu CS, Chaubey A, Phelan JD, Horman SR, Wunderlich M, Guzman ML, Jegga AG, Zeleznik-Le NJ, Chen J, Mulloy JC, Cancelas JA, Jordan CT, Aronow BJ, Marcucci G, Bhat B, Gebelein B, Grimes HL. Velu CS, et al. Among authors: grimes hl. J Clin Invest. 2014 Jan;124(1):222-36. doi: 10.1172/JCI66005. Epub 2013 Dec 16. J Clin Invest. 2014. PMID: 24334453 Free PMC article.
139 results