Gunn-Moore FJ - Search Results

1

Is amyloid binding alcohol dehydrogenase a drug target for treating Alzheimer's disease?

Borger E, Aitken L, Du H, Zhang W, Gunn-Moore FJ, Yan SS. Borger E, et al. Curr Alzheimer Res. 2013 Jan;10(1):21-9. Curr Alzheimer Res. 2013. PMID: 22742981 Free PMC article. Review.

2

The consequences of mitochondrial amyloid beta-peptide in Alzheimer's disease.

Muirhead KE, Borger E, Aitken L, Conway SJ, Gunn-Moore FJ. Muirhead KE, et al. Biochem J. 2010 Feb 24;426(3):255-70. doi: 10.1042/BJ20091941. Biochem J. 2010. PMID: 20175748 Review.

3

Mitochondrial β-amyloid in Alzheimer's disease.

Borger E, Aitken L, Muirhead KE, Allen ZE, Ainge JA, Conway SJ, Gunn-Moore FJ. Borger E, et al. Biochem Soc Trans. 2011 Aug;39(4):868-73. doi: 10.1042/BST0390868. Biochem Soc Trans. 2011. PMID: 21787315

4

Morphology-Specific Inhibition of β-Amyloid Aggregates by 17β-Hydroxysteroid Dehydrogenase Type 10.

Aitken L, Quinn SD, Perez-Gonzalez C, Samuel ID, Penedo JC, Gunn-Moore FJ. Aitken L, et al. Chembiochem. 2016 Jun 2;17(11):1029-37. doi: 10.1002/cbic.201600081. Epub 2016 Apr 25. Chembiochem. 2016. PMID: 26991863 Free article.

5

Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer's disease.

Yu Q, Wang Y, Du F, Yan S, Hu G, Origlia N, Rutigliano G, Sun Q, Yu H, Ainge J, Yan SF, Gunn-Moore F, Yan SS. Yu Q, et al. Nat Commun. 2018 Jul 30;9(1):2968. doi: 10.1038/s41467-018-04389-0. Nat Commun. 2018. PMID: 30061577 Free PMC article.

6

Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment.

Hroch L, Benek O, Guest P, Aitken L, Soukup O, Janockova J, Musil K, Dohnal V, Dolezal R, Kuca K, Smith TK, Gunn-Moore F, Musilek K. Hroch L, et al. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3675-8. doi: 10.1016/j.bmcl.2016.05.087. Epub 2016 May 30. Bioorg Med Chem Lett. 2016. PMID: 27287370

7

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment.

Hroch L, Guest P, Benek O, Soukup O, Janockova J, Dolezal R, Kuca K, Aitken L, Smith TK, Gunn-Moore F, Zala D, Ramsay RR, Musilek K. Hroch L, et al. Bioorg Med Chem. 2017 Feb 1;25(3):1143-1152. doi: 10.1016/j.bmc.2016.12.029. Epub 2016 Dec 27. Bioorg Med Chem. 2017. PMID: 28082069

8

1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders.

Benek O, Hroch L, Aitken L, Gunn-Moore F, Vinklarova L, Kuca K, Perez DI, Perez C, Martinez A, Fisar Z, Musilek K. Benek O, et al. J Enzyme Inhib Med Chem. 2018 Dec;33(1):665-670. doi: 10.1080/14756366.2018.1445736. J Enzyme Inhib Med Chem. 2018. PMID: 29536773 Free PMC article.

9

Willin/FRMD6 Mediates Mitochondrial Dysfunction Relevant to Neuronal Aβ Toxicity.

Chen D, Yu W, Aitken L, Gunn-Moore F. Chen D, et al. Cells. 2022 Oct 6;11(19):3140. doi: 10.3390/cells11193140. Cells. 2022. PMID: 36231104 Free PMC article.

10

Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment.

Schmidt M, Benek O, Vinklarova L, Hrabinova M, Zemanova L, Chribek M, Kralova V, Hroch L, Dolezal R, Lycka A, Prchal L, Jun D, Aitken L, Gunn-Moore F, Kuca K, Musilek K. Schmidt M, et al. Int J Mol Sci. 2020 Mar 17;21(6):2059. doi: 10.3390/ijms21062059. Int J Mol Sci. 2020. PMID: 32192199 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

116 results

Search Page

Filters