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Page 1
Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors.
Zhang X, Inukai T, Hirose K, Akahane K, Kuroda I, Honna-Oshiro H, Kagami K, Goi K, Nakamura K, Kobayashi M, Endo M, Yagita H, Kurosawa H, Thomas Look A, Honda H, Inaba T, Nakazawa S, Sugita K. Zhang X, et al. Among authors: kurosawa h. Leukemia. 2012 Dec;26(12):2483-93. doi: 10.1038/leu.2012.139. Epub 2012 May 30. Leukemia. 2012. PMID: 22743623
Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).
Hirose K, Inukai T, Kikuchi J, Furukawa Y, Ikawa T, Kawamoto H, Oram SH, Göttgens B, Kiyokawa N, Miyagawa Y, Okita H, Akahane K, Zhang X, Kuroda I, Honna H, Kagami K, Goi K, Kurosawa H, Look AT, Matsui H, Inaba T, Sugita K. Hirose K, et al. Among authors: kurosawa h. Blood. 2010 Aug 12;116(6):962-70. doi: 10.1182/blood-2009-09-244673. Epub 2010 Jun 2. Blood. 2010. PMID: 20519628 Free article.
Hypercalcemia in childhood acute lymphoblastic leukemia: frequent implication of parathyroid hormone-related peptide and E2A-HLF from translocation 17;19.
Inukai T, Hirose K, Inaba T, Kurosawa H, Hama A, Inada H, Chin M, Nagatoshi Y, Ohtsuka Y, Oda M, Goto H, Endo M, Morimoto A, Imaizumi M, Kawamura N, Miyajima Y, Ohtake M, Miyaji R, Saito M, Tawa A, Yanai F, Goi K, Nakazawa S, Sugita K. Inukai T, et al. Among authors: kurosawa h. Leukemia. 2007 Feb;21(2):288-96. doi: 10.1038/sj.leu.2404496. Epub 2006 Dec 21. Leukemia. 2007. PMID: 17183364
Specific induction of CD33 expression by E2A-HLF: the first evidence for aberrant myeloid antigen expression in ALL by a fusion transcription factor.
Akahane K, Inukai T, Inaba T, Kurosawa H, Look AT, Kiyokawa N, Fujimoto J, Goto H, Endo M, Zhang X, Hirose K, Kuroda I, Honna H, Kagami K, Goi K, Nakazawa S, Sugita K. Akahane K, et al. Among authors: kurosawa h. Leukemia. 2010 Apr;24(4):865-9. doi: 10.1038/leu.2010.8. Epub 2010 Feb 11. Leukemia. 2010. PMID: 20147975 No abstract available.
Two candidate downstream target genes for E2A-HLF.
Kurosawa H, Goi K, Inukai T, Inaba T, Chang KS, Shinjyo T, Rakestraw KM, Naeve CW, Look AT. Kurosawa H, et al. Blood. 1999 Jan 1;93(1):321-32. Blood. 1999. PMID: 9864177 Free article.
11;13 translocation in acute nonlymphocytic leukemia.
Sugita K, Kurosawa H, Sakakibara H, Eguchi M, Furukawa T, Hanada R. Sugita K, et al. Among authors: kurosawa h. Acta Haematol. 1992;87(4):198-201. doi: 10.1159/000204767. Acta Haematol. 1992. PMID: 1519435
1,075 results