Santos DS - Search Results

1

Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS?

Breda A, Martinelli LK, Bizarro CV, Rosado LA, Borges CB, Santos DS, Basso LA. Breda A, et al. Among authors: santos ds. PLoS One. 2012;7(6):e39245. doi: 10.1371/journal.pone.0039245. Epub 2012 Jun 20. PLoS One. 2012. PMID: 22745722 Free PMC article.

2

Substrate specificity and kinetic mechanism of purine nucleoside phosphorylase from Mycobacterium tuberculosis.

Ducati RG, Santos DS, Basso LA. Ducati RG, et al. Among authors: santos ds. Arch Biochem Biophys. 2009 Jun 15;486(2):155-64. doi: 10.1016/j.abb.2009.04.011. Epub 2009 May 3. Arch Biochem Biophys. 2009. PMID: 19416718 Free article.

3

UMP kinase from Mycobacterium tuberculosis: Mode of action and allosteric interactions, and their likely role in pyrimidine metabolism regulation.

Rostirolla DC, Breda A, Rosado LA, Palma MS, Basso LA, Santos DS. Rostirolla DC, et al. Among authors: santos ds. Arch Biochem Biophys. 2011 Jan 15;505(2):202-12. doi: 10.1016/j.abb.2010.10.019. Epub 2010 Oct 28. Arch Biochem Biophys. 2011. PMID: 21035424 Free article.

4

Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosis hisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23).

Nunes JE, Ducati RG, Breda A, Rosado LA, de Souza BM, Palma MS, Santos DS, Basso LA. Nunes JE, et al. Among authors: santos ds. Arch Biochem Biophys. 2011 Aug 15;512(2):143-53. doi: 10.1016/j.abb.2011.05.020. Epub 2011 Jun 6. Arch Biochem Biophys. 2011. PMID: 21672513 Free article.

5

Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA).

Rosado LA, Caceres RA, de Azevedo WF Jr, Basso LA, Santos DS. Rosado LA, et al. Among authors: santos ds. BMC Res Notes. 2012 Sep 25;5:526. doi: 10.1186/1756-0500-5-526. BMC Res Notes. 2012. PMID: 23006410 Free PMC article.

6

Kinetic mechanism determination and analysis of metal requirement of dehydroquinate synthase from Mycobacterium tuberculosis H37Rv: an essential step in the function-based rational design of anti-TB drugs.

de Mendonça JD, Adachi O, Rosado LA, Ducati RG, Santos DS, Basso LA. de Mendonça JD, et al. Among authors: santos ds. Mol Biosyst. 2011 Jan;7(1):119-28. doi: 10.1039/c0mb00085j. Epub 2010 Oct 26. Mol Biosyst. 2011. PMID: 20978656

7

Molecular, kinetic and thermodynamic characterization of Mycobacterium tuberculosis orotate phosphoribosyltransferase.

Breda A, Rosado LA, Lorenzini DM, Basso LA, Santos DS. Breda A, et al. Among authors: santos ds. Mol Biosyst. 2012 Feb;8(2):572-86. doi: 10.1039/c1mb05402c. Epub 2011 Nov 11. Mol Biosyst. 2012. PMID: 22075667

8

Pyrimidin-2(1H)-ones based inhibitors of Mycobacterium tuberculosis orotate phosphoribosyltransferase.

Breda A, Machado P, Rosado LA, Souto AA, Santos DS, Basso LA. Breda A, et al. Among authors: santos ds. Eur J Med Chem. 2012 Aug;54:113-22. doi: 10.1016/j.ejmech.2012.04.031. Epub 2012 Apr 30. Eur J Med Chem. 2012. PMID: 22608674

9

Biochemical characterization of uracil phosphoribosyltransferase from Mycobacterium tuberculosis.

Villela AD, Ducati RG, Rosado LA, Bloch CJ, Prates MV, Gonçalves DC, Ramos CH, Basso LA, Santos DS. Villela AD, et al. Among authors: santos ds. PLoS One. 2013;8(2):e56445. doi: 10.1371/journal.pone.0056445. Epub 2013 Feb 12. PLoS One. 2013. PMID: 23424660 Free PMC article.

10

The mode of action of recombinant Mycobacterium tuberculosis shikimate kinase: kinetics and thermodynamics analyses.

Rosado LA, Vasconcelos IB, Palma MS, Frappier V, Najmanovich RJ, Santos DS, Basso LA. Rosado LA, et al. Among authors: santos ds. PLoS One. 2013 May 6;8(5):e61918. doi: 10.1371/journal.pone.0061918. Print 2013. PLoS One. 2013. PMID: 23671579 Free PMC article.

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