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Page 1
Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection.
Rodrigues-Junior VS, Dos Santos Junior A, Dos Santos AJ, Schneider CZ, Calixto JB, Sousa EH, de França Lopes LG, Souto AA, Basso LA, Santos DS, Campos MM. Rodrigues-Junior VS, et al. Among authors: sousa eh. Int J Antimicrob Agents. 2012 Aug;40(2):182-5. doi: 10.1016/j.ijantimicag.2012.04.019. Epub 2012 Jun 27. Int J Antimicrob Agents. 2012. PMID: 22748570
Synthesis and mechanistic investigation of iron(II) complexes of isoniazid and derivatives as a redox-mediated activation strategy for anti-tuberculosis therapy.
Laborde J, Deraeve C, de Mesquita Vieira FG, Sournia-Saquet A, Rechignat L, Villela AD, Abbadi BL, Macchi FS, Pissinate K, Bizarro CV, Machado P, Basso LA, Pratviel G, de França Lopes LG, Sousa EHS, Bernardes-Génisson V. Laborde J, et al. J Inorg Biochem. 2018 Feb;179:71-81. doi: 10.1016/j.jinorgbio.2017.11.013. Epub 2017 Nov 21. J Inorg Biochem. 2018. PMID: 29175704
Pentacyanoferrate(II) complex of pyridine-4- and pyrazine-2-hydroxamic acid as source of HNO: investigation of anti-tubercular and vasodilation activities.
Carvalho EM, de Freitas Paulo T, Saquet AS, Abbadi BL, Macchi FS, Bizarro CV, de Morais Campos R, Ferreira TLA, do Nascimento NRF, Lopes LGF, Chauvin R, Sousa EHS, Bernardes-Génisson V. Carvalho EM, et al. J Biol Inorg Chem. 2020 Sep;25(6):887-901. doi: 10.1007/s00775-020-01805-z. Epub 2020 Jul 29. J Biol Inorg Chem. 2020. PMID: 32728907
The biofilm inhibition activity of a NO donor nanosilica with enhanced antibiotics action.
da Silva Filho PM, Andrade AL, Lopes JBAC, Pinheiro AA, de Vasconcelos MA, Fonseca SGDC, Lopes LGF, Sousa EHS, Teixeira EH, Longhinotti E. da Silva Filho PM, et al. Among authors: sousa ehs. Int J Pharm. 2021 Dec 15;610:121220. doi: 10.1016/j.ijpharm.2021.121220. Epub 2021 Oct 20. Int J Pharm. 2021. PMID: 34687814 Free article.
Anti-asthmatic effect of nitric oxide metallo-donor FOR811A [cis-[Ru(bpy)2(2-MIM)(NO)](PF6)3] in the respiratory mechanics of Swiss mice.
Costa PPC, Waller SB, Dos Santos GR, Gondim FL, Serra DS, Cavalcante FSÁ, Gouveia Júnior FS, de Paula Júnior VF, Sousa EHS, Lopes LGF, Ribeiro WLC, Monteiro HSA. Costa PPC, et al. PLoS One. 2021 Mar 12;16(3):e0248394. doi: 10.1371/journal.pone.0248394. eCollection 2021. PLoS One. 2021. PMID: 33711054 Free PMC article.
A divergent mode of activation of a nitrosyl iron complex with unusual antiangiogenic activity.
Carvalho EM, Ridnour LA, Júnior FSG, Cabral PHB, do Nascimento NRF, Wink DA, Franco DW, de Medeiros MJC, de Lima Pontes D, Longhinotti E, de Freitas Paulo T, Bernardes-Génisson V, Chauvin R, Sousa EHS, Lopes LGF. Carvalho EM, et al. J Inorg Biochem. 2020 Sep;210:111133. doi: 10.1016/j.jinorgbio.2020.111133. Epub 2020 Jun 20. J Inorg Biochem. 2020. PMID: 32619898 Free PMC article.
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