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75 results

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Evidence for the ubiquitin protease UBP43 as an antineoplastic target.
Guo Y, Chinyengetere F, Dolinko AV, Lopez-Aguiar A, Lu Y, Galimberti F, Ma T, Feng Q, Sekula D, Freemantle SJ, Andrew AS, Memoli V, Dmitrovsky E. Guo Y, et al. Among authors: freemantle sj. Mol Cancer Ther. 2012 Sep;11(9):1968-77. doi: 10.1158/1535-7163.MCT-12-0248. Epub 2012 Jul 2. Mol Cancer Ther. 2012. PMID: 22752428 Free PMC article.
Blockade of the ubiquitin protease UBP43 destabilizes transcription factor PML/RARα and inhibits the growth of acute promyelocytic leukemia.
Guo Y, Dolinko AV, Chinyengetere F, Stanton B, Bomberger JM, Demidenko E, Zhou DC, Gallagher R, Ma T, Galimberti F, Liu X, Sekula D, Freemantle S, Dmitrovsky E. Guo Y, et al. Cancer Res. 2010 Dec 1;70(23):9875-85. doi: 10.1158/0008-5472.CAN-10-1100. Epub 2010 Oct 8. Cancer Res. 2010. PMID: 20935222 Free PMC article.
CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110.
Hu S, Danilov AV, Godek K, Orr B, Tafe LJ, Rodriguez-Canales J, Behrens C, Mino B, Moran CA, Memoli VA, Mustachio LM, Galimberti F, Ravi S, DeCastro A, Lu Y, Sekula D, Andrew AS, Wistuba II, Freemantle S, Compton DA, Dmitrovsky E. Hu S, et al. Cancer Res. 2015 May 15;75(10):2029-38. doi: 10.1158/0008-5472.CAN-14-1494. Epub 2015 Mar 25. Cancer Res. 2015. PMID: 25808870 Free PMC article.
Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations.
Galimberti F, Busch AM, Chinyengetere F, Ma T, Sekula D, Memoli VA, Dragnev KH, Liu F, Johnson KC, Guo Y, Freemantle SJ, Andrew AS, Greninger P, Robbins DJ, Settleman J, Benes C, Dmitrovsky E. Galimberti F, et al. Among authors: freemantle sj. Int J Oncol. 2012 Nov;41(5):1751-61. doi: 10.3892/ijo.2012.1599. Epub 2012 Aug 22. Int J Oncol. 2012. PMID: 22923130 Free PMC article.
Evidence for tankyrases as antineoplastic targets in lung cancer.
Busch AM, Johnson KC, Stan RV, Sanglikar A, Ahmed Y, Dmitrovsky E, Freemantle SJ. Busch AM, et al. Among authors: freemantle sj. BMC Cancer. 2013 Apr 28;13:211. doi: 10.1186/1471-2407-13-211. BMC Cancer. 2013. PMID: 23621985 Free PMC article.
Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer.
Ma T, Galimberti F, Erkmen CP, Memoli V, Chinyengetere F, Sempere L, Beumer JH, Anyang BN, Nugent W, Johnstone D, Tsongalis GJ, Kurie JM, Li H, Direnzo J, Guo Y, Freemantle SJ, Dragnev KH, Dmitrovsky E. Ma T, et al. Among authors: freemantle sj. Mol Cancer Ther. 2013 Aug;12(8):1545-55. doi: 10.1158/1535-7163.MCT-12-0933. Epub 2013 May 16. Mol Cancer Ther. 2013. PMID: 23686769 Free PMC article.
75 results