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The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.
Nielsen CF, van Putten SM, Lund IK, Melander MC, Nørregaard KS, Jürgensen HJ, Reckzeh K, Christensen KR, Ingvarsen SZ, Gårdsvoll H, Jensen KE, Hamerlik P, Engelholm LH, Behrendt N. Nielsen CF, et al. Among authors: ingvarsen sz. Oncotarget. 2017 Jul 4;8(27):44605-44624. doi: 10.18632/oncotarget.17883. Oncotarget. 2017. PMID: 28574834 Free PMC article.
Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180.
Engelholm LH, Melander MC, Hald A, Persson M, Madsen DH, Jürgensen HJ, Johansson K, Nielsen C, Nørregaard KS, Ingvarsen SZ, Kjaer A, Trovik CS, Laerum OD, Bugge TH, Eide J, Behrendt N. Engelholm LH, et al. Among authors: ingvarsen sz. J Pathol. 2016 Jan;238(1):120-33. doi: 10.1002/path.4661. Epub 2015 Nov 30. J Pathol. 2016. PMID: 26466547
The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1.
Nørregaard KS, Jürgensen HJ, Ingvarsen SZ, Heltberg SS, Hagensen CE, Gårdsvoll H, Madsen DH, Jensen ON, Engelholm LH, Behrendt N. Nørregaard KS, et al. Among authors: ingvarsen sz. Matrix Biol. 2022 Aug;111:307-328. doi: 10.1016/j.matbio.2022.07.004. Epub 2022 Jul 22. Matrix Biol. 2022. PMID: 35878760 Free article.
Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.
Madsen DH, Engelholm LH, Ingvarsen S, Hillig T, Wagenaar-Miller RA, Kjøller L, Gårdsvoll H, Høyer-Hansen G, Holmbeck K, Bugge TH, Behrendt N. Madsen DH, et al. Among authors: ingvarsen s. J Biol Chem. 2007 Sep 14;282(37):27037-27045. doi: 10.1074/jbc.M701088200. Epub 2007 Jul 9. J Biol Chem. 2007. PMID: 17623673 Free article.
The collagen receptor uPARAP/Endo180.
Engelholm LH, Ingvarsen S, Jürgensen HJ, Hillig T, Madsen DH, Nielsen BS, Behrendt N. Engelholm LH, et al. Among authors: ingvarsen s. Front Biosci (Landmark Ed). 2009 Jan 1;14(6):2103-14. doi: 10.2741/3365. Front Biosci (Landmark Ed). 2009. PMID: 19273187 Free article. Review.
The non-phagocytic route of collagen uptake: a distinct degradation pathway.
Madsen DH, Ingvarsen S, Jürgensen HJ, Melander MC, Kjøller L, Moyer A, Honoré C, Madsen CA, Garred P, Burgdorf S, Bugge TH, Behrendt N, Engelholm LH. Madsen DH, et al. Among authors: ingvarsen s. J Biol Chem. 2011 Jul 29;286(30):26996-7010. doi: 10.1074/jbc.M110.208033. Epub 2011 Jun 7. J Biol Chem. 2011. PMID: 21652704 Free PMC article.
20 results