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Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.
van Schouwenburg PA, van de Stadt LA, de Jong RN, van Buren EE, Kruithof S, de Groot E, Hart M, van Ham SM, Rispens T, Aarden L, Wolbink GJ, Wouters D. van Schouwenburg PA, et al. Among authors: van ham sm, van de stadt la, van buren ee. Ann Rheum Dis. 2013 Jan;72(1):104-9. doi: 10.1136/annrheumdis-2012-201445. Epub 2012 Jul 3. Ann Rheum Dis. 2013. PMID: 22759910
The presence or absence of antibodies to infliximab or adalimumab determines the outcome of switching to etanercept.
Jamnitski A, Bartelds GM, Nurmohamed MT, van Schouwenburg PA, van Schaardenburg D, Stapel SO, Dijkmans BA, Aarden L, Wolbink GJ. Jamnitski A, et al. Among authors: van schouwenburg pa, van schaardenburg d. Ann Rheum Dis. 2011 Feb;70(2):284-8. doi: 10.1136/ard.2010.135111. Epub 2010 Nov 10. Ann Rheum Dis. 2011. PMID: 21068090 Clinical Trial.
Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies.
van Schouwenburg PA, Kruithof S, Votsmeier C, van Schie K, Hart MH, de Jong RN, van Buren EE, van Ham M, Aarden L, Wolbink G, Wouters D, Rispens T. van Schouwenburg PA, et al. Among authors: van schie k, van ham m, van buren ee. J Biol Chem. 2014 Dec 12;289(50):34482-8. doi: 10.1074/jbc.M114.615500. Epub 2014 Oct 17. J Biol Chem. 2014. PMID: 25326381 Free PMC article. Review.
Monoclonal anti-citrullinated protein antibodies selected on citrullinated fibrinogen have distinct targets with different cross-reactivity patterns.
van de Stadt LA, van Schouwenburg PA, Bryde S, Kruithof S, van Schaardenburg D, Hamann D, Wolbink G, Rispens T. van de Stadt LA, et al. Among authors: van schouwenburg pa, van schaardenburg d. Rheumatology (Oxford). 2013 Apr;52(4):631-5. doi: 10.1093/rheumatology/kes371. Epub 2012 Dec 22. Rheumatology (Oxford). 2013. PMID: 23264551
32 results