Begley TJ - Search Results

1

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins.

Chan CT, Pang YL, Deng W, Babu IR, Dyavaiah M, Begley TJ, Dedon PC. Chan CT, et al. Among authors: begley tj. Nat Commun. 2012 Jul 3;3:937. doi: 10.1038/ncomms1938. Nat Commun. 2012. PMID: 22760636 Free PMC article.

2

The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA.

Fry RC, DeMott MS, Cosgrove JP, Begley TJ, Samson LD, Dedon PC. Fry RC, et al. Among authors: begley tj. BMC Genomics. 2006 Dec 12;7:313. doi: 10.1186/1471-2164-7-313. BMC Genomics. 2006. PMID: 17163986 Free PMC article.

3

Trm9-catalyzed tRNA modifications link translation to the DNA damage response.

Begley U, Dyavaiah M, Patil A, Rooney JP, DiRenzo D, Young CM, Conklin DS, Zitomer RS, Begley TJ. Begley U, et al. Among authors: begley tj. Mol Cell. 2007 Dec 14;28(5):860-70. doi: 10.1016/j.molcel.2007.09.021. Mol Cell. 2007. PMID: 18082610 Free PMC article.

4

Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.

Fu D, Brophy JA, Chan CT, Atmore KA, Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD. Fu D, et al. Among authors: begley tj, begley u. Mol Cell Biol. 2010 May;30(10):2449-59. doi: 10.1128/MCB.01604-09. Epub 2010 Mar 22. Mol Cell Biol. 2010. PMID: 20308323 Free PMC article.

5

A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.

Chan CT, Dyavaiah M, DeMott MS, Taghizadeh K, Dedon PC, Begley TJ. Chan CT, et al. Among authors: begley tj. PLoS Genet. 2010 Dec 16;6(12):e1001247. doi: 10.1371/journal.pgen.1001247. PLoS Genet. 2010. PMID: 21187895 Free PMC article.

6

Autophagy-dependent regulation of the DNA damage response protein ribonucleotide reductase 1.

Dyavaiah M, Rooney JP, Chittur SV, Lin Q, Begley TJ. Dyavaiah M, et al. Among authors: begley tj. Mol Cancer Res. 2011 Apr;9(4):462-75. doi: 10.1158/1541-7786.MCR-10-0473. Epub 2011 Feb 22. Mol Cancer Res. 2011. PMID: 21343333

7

The gene-specific codon counting database: a genome-based catalog of one-, two-, three-, four- and five-codon combinations present in Saccharomyces cerevisiae genes.

Tumu S, Patil A, Towns W, Dyavaiah M, Begley TJ. Tumu S, et al. Among authors: begley tj. Database (Oxford). 2012 Feb 8;2012:bas002. doi: 10.1093/database/bas002. Print 2012. Database (Oxford). 2012. PMID: 22323063 Free PMC article.

8

Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications.

Patil A, Chan CT, Dyavaiah M, Rooney JP, Dedon PC, Begley TJ. Patil A, et al. Among authors: begley tj. RNA Biol. 2012 Jul;9(7):990-1001. doi: 10.4161/rna.20531. Epub 2012 Jul 1. RNA Biol. 2012. PMID: 22832247 Free PMC article.

9

Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response.

Patil A, Dyavaiah M, Joseph F, Rooney JP, Chan CT, Dedon PC, Begley TJ. Patil A, et al. Among authors: begley tj. Cell Cycle. 2012 Oct 1;11(19):3656-65. doi: 10.4161/cc.21919. Epub 2012 Aug 30. Cell Cycle. 2012. PMID: 22935709 Free PMC article.

10

A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α.

Begley U, Sosa MS, Avivar-Valderas A, Patil A, Endres L, Estrada Y, Chan CT, Su D, Dedon PC, Aguirre-Ghiso JA, Begley T. Begley U, et al. EMBO Mol Med. 2013 Mar;5(3):366-83. doi: 10.1002/emmm.201201161. Epub 2013 Feb 4. EMBO Mol Med. 2013. PMID: 23381944 Free PMC article.

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