Dedon PC - Search Results

1

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins.

Chan CT, Pang YL, Deng W, Babu IR, Dyavaiah M, Begley TJ, Dedon PC. Chan CT, et al. Among authors: dedon pc. Nat Commun. 2012 Jul 3;3:937. doi: 10.1038/ncomms1938. Nat Commun. 2012. PMID: 22760636 Free PMC article.

2

The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA.

Fry RC, DeMott MS, Cosgrove JP, Begley TJ, Samson LD, Dedon PC. Fry RC, et al. Among authors: dedon pc. BMC Genomics. 2006 Dec 12;7:313. doi: 10.1186/1471-2164-7-313. BMC Genomics. 2006. PMID: 17163986 Free PMC article.

3

Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.

Fu D, Brophy JA, Chan CT, Atmore KA, Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD. Fu D, et al. Among authors: dedon pc. Mol Cell Biol. 2010 May;30(10):2449-59. doi: 10.1128/MCB.01604-09. Epub 2010 Mar 22. Mol Cell Biol. 2010. PMID: 20308323 Free PMC article.

4

A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.

Chan CT, Dyavaiah M, DeMott MS, Taghizadeh K, Dedon PC, Begley TJ. Chan CT, et al. Among authors: dedon pc. PLoS Genet. 2010 Dec 16;6(12):e1001247. doi: 10.1371/journal.pgen.1001247. PLoS Genet. 2010. PMID: 21187895 Free PMC article.

5

Identification of N6,N6-dimethyladenosine in transfer RNA from Mycobacterium bovis Bacille Calmette-Guérin.

Chan CT, Chionh YH, Ho CH, Lim KS, Babu IR, Ang E, Wenwei L, Alonso S, Dedon PC. Chan CT, et al. Among authors: dedon pc. Molecules. 2011 Jun 21;16(6):5168-81. doi: 10.3390/molecules16065168. Molecules. 2011. PMID: 21694680 Free PMC article.

6

Sequence-dependent variation in the reactivity of 8-Oxo-7,8-dihydro-2'-deoxyguanosine toward oxidation.

Lim KS, Taghizadeh K, Wishnok JS, Babu IR, Shafirovich V, Geacintov NE, Dedon PC. Lim KS, et al. Among authors: dedon pc. Chem Res Toxicol. 2012 Feb 20;25(2):366-73. doi: 10.1021/tx200422g. Epub 2011 Dec 2. Chem Res Toxicol. 2012. PMID: 22103813 Free PMC article.

7

Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications.

Patil A, Chan CT, Dyavaiah M, Rooney JP, Dedon PC, Begley TJ. Patil A, et al. Among authors: dedon pc. RNA Biol. 2012 Jul;9(7):990-1001. doi: 10.4161/rna.20531. Epub 2012 Jul 1. RNA Biol. 2012. PMID: 22832247 Free PMC article.

8

Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response.

Patil A, Dyavaiah M, Joseph F, Rooney JP, Chan CT, Dedon PC, Begley TJ. Patil A, et al. Among authors: dedon pc. Cell Cycle. 2012 Oct 1;11(19):3656-65. doi: 10.4161/cc.21919. Epub 2012 Aug 30. Cell Cycle. 2012. PMID: 22935709 Free PMC article.

9

In situ analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine oxidation reveals sequence- and agent-specific damage spectra.

Lim KS, Cui L, Taghizadeh K, Wishnok JS, Chan W, DeMott MS, Babu IR, Tannenbaum SR, Dedon PC. Lim KS, et al. Among authors: dedon pc. J Am Chem Soc. 2012 Oct 31;134(43):18053-64. doi: 10.1021/ja307525h. Epub 2012 Oct 22. J Am Chem Soc. 2012. PMID: 23057664 Free PMC article.

10

A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α.

Begley U, Sosa MS, Avivar-Valderas A, Patil A, Endres L, Estrada Y, Chan CT, Su D, Dedon PC, Aguirre-Ghiso JA, Begley T. Begley U, et al. Among authors: dedon pc. EMBO Mol Med. 2013 Mar;5(3):366-83. doi: 10.1002/emmm.201201161. Epub 2013 Feb 4. EMBO Mol Med. 2013. PMID: 23381944 Free PMC article.

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