Benkovic SJ - Search Results

1

Targeting tumour proliferation with a small-molecule inhibitor of AICAR transformylase homodimerization.

Spurr IB, Birts CN, Cuda F, Benkovic SJ, Blaydes JP, Tavassoli A. Spurr IB, et al. Among authors: benkovic sj. Chembiochem. 2012 Jul 23;13(11):1628-34. doi: 10.1002/cbic.201200279. Epub 2012 Jul 4. Chembiochem. 2012. PMID: 22764122 Free PMC article.

2

Split-intein mediated circular ligation used in the synthesis of cyclic peptide libraries in E. coli.

Tavassoli A, Benkovic SJ. Tavassoli A, et al. Among authors: benkovic sj. Nat Protoc. 2007;2(5):1126-33. doi: 10.1038/nprot.2007.152. Nat Protoc. 2007. PMID: 17546003

3

Genetic selection of cyclic peptide Dam methyltransferase inhibitors.

Naumann TA, Tavassoli A, Benkovic SJ. Naumann TA, et al. Among authors: benkovic sj. Chembiochem. 2008 Jan 25;9(2):194-7. doi: 10.1002/cbic.200700561. Chembiochem. 2008. PMID: 18085543 No abstract available.

4

Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction.

Tavassoli A, Lu Q, Gam J, Pan H, Benkovic SJ, Cohen SN. Tavassoli A, et al. Among authors: benkovic sj. ACS Chem Biol. 2008 Dec 19;3(12):757-64. doi: 10.1021/cb800193n. ACS Chem Biol. 2008. PMID: 19053244

5

10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase.

Marsilje TH, Hedrick MP, Desharnais J, Capps K, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Marsilje TH, et al. Among authors: benkovic sj. Bioorg Med Chem. 2003 Oct 1;11(20):4503-9. doi: 10.1016/s0968-0896(03)00457-7. Bioorg Med Chem. 2003. PMID: 13129586

6

Genetically selected cyclic-peptide inhibitors of AICAR transformylase homodimerization.

Tavassoli A, Benkovic SJ. Tavassoli A, et al. Among authors: benkovic sj. Angew Chem Int Ed Engl. 2005 Apr 29;44(18):2760-2763. doi: 10.1002/anie.200500417. Angew Chem Int Ed Engl. 2005. PMID: 15830403 No abstract available.

7

Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase.

Marsilje TH, Hedrick MP, Desharnais J, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Marsilje TH, et al. Among authors: benkovic sj. Bioorg Med Chem. 2003 Oct 1;11(20):4487-501. doi: 10.1016/s0968-0896(03)00456-5. Bioorg Med Chem. 2003. PMID: 13129585

8

Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.

Cheng H, Chong Y, Hwang I, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Cheng H, et al. Among authors: benkovic sj. Bioorg Med Chem. 2005 May 16;13(10):3577-85. doi: 10.1016/j.bmc.2004.12.004. Bioorg Med Chem. 2005. PMID: 15848770

9

Hypoxia drives the assembly of the multienzyme purinosome complex.

Doigneaux C, Pedley AM, Mistry IN, Papayova M, Benkovic SJ, Tavassoli A. Doigneaux C, et al. Among authors: benkovic sj. J Biol Chem. 2020 Jul 10;295(28):9551-9566. doi: 10.1074/jbc.RA119.012175. Epub 2020 May 21. J Biol Chem. 2020. PMID: 32439803 Free PMC article.

10

Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.

Desharnais J, Hwang I, Zhang Y, Tavassoli A, Baboval J, Benkovic SJ, Wilson IA, Boger DL. Desharnais J, et al. Among authors: benkovic sj. Bioorg Med Chem. 2003 Oct 1;11(20):4511-21. doi: 10.1016/s0968-0896(03)00458-9. Bioorg Med Chem. 2003. PMID: 13129587

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