β-Catenin modulation in neurofibromatosis type 1 bone repair: therapeutic implications.
Ghadakzadeh S, Kannu P, Whetstone H, Howard A, Alman BA.
Ghadakzadeh S, et al. Among authors: whetstone h.
FASEB J. 2016 Sep;30(9):3227-37. doi: 10.1096/fj.201500190RR. Epub 2016 Jun 15.
FASEB J. 2016.
PMID: 27306335
An up-regulation of beta-catenin in NF1 causes a shift away from osteoblastic differentiation resulting in a pseudarthrosis in vivo These results support the notion that pharmacological modulation of beta-catenin can be used to treat pseudarthrosis in patients with NF1.-Ghadakzad …
An up-regulation of beta-catenin in NF1 causes a shift away from osteoblastic differentiation resulting in a pseudarthrosis in vivo These re …