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Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease.
Maalej E, Chabchoub F, Oset-Gasque MJ, Esquivias-Pérez M, González MP, Monjas L, Pérez C, de los Ríos C, Rodríguez-Franco MI, Iriepa I, Moraleda I, Chioua M, Romero A, Marco-Contelles J, Samadi A. Maalej E, et al. Among authors: gonzalez mp. Eur J Med Chem. 2012 Aug;54:750-63. doi: 10.1016/j.ejmech.2012.06.038. Epub 2012 Jun 28. Eur J Med Chem. 2012. PMID: 22795665
Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.
Chioua M, Sucunza D, Soriano E, Hadjipavlou-Litina D, Alcázar A, Ayuso I, Oset-Gasque MJ, González MP, Monjas L, Rodríguez-Franco MI, Marco-Contelles J, Samadi A. Chioua M, et al. Among authors: gonzalez mp. J Med Chem. 2012 Jan 12;55(1):153-68. doi: 10.1021/jm201105a. Epub 2011 Dec 21. J Med Chem. 2012. PMID: 22126405
Toxicological and pharmacological evaluation, antioxidant, ADMET and molecular modeling of selected racemic chromenotacrines {11-amino-12-aryl-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ols} for the potential prevention and treatment of Alzheimer's disease.
Oset-Gasque MJ, González MP, Pérez-Peña J, García-Font N, Romero A, del Pino J, Ramos E, Hadjipavlou-Litina D, Soriano E, Chioua M, Samadi A, Raghuvanshi DS, Singh KN, Marco-Contelles J. Oset-Gasque MJ, et al. Among authors: gonzalez mp. Eur J Med Chem. 2014 Mar 3;74:491-501. doi: 10.1016/j.ejmech.2013.12.021. Epub 2014 Jan 8. Eur J Med Chem. 2014. PMID: 24502897
233 results