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Contrasting Nav1.8 Activity in Scn10a-/- Ventricular Myocytes and the Intact Heart.
Stroud DM, Yang T, Bersell K, Kryshtal DO, Nagao S, Shaffer C, Short L, Hall L, Atack TC, Zhang W, Knollmann BC, Baudenbacher F, Roden DM. Stroud DM, et al. Among authors: knollmann bc. J Am Heart Assoc. 2016 Nov 2;5(11):e002946. doi: 10.1161/JAHA.115.002946. J Am Heart Assoc. 2016. PMID: 27806966 Free PMC article.
The Purkinje-myocardial junction is the anatomic origin of ventricular arrhythmia in CPVT.
Blackwell DJ, Faggioni M, Wleklinski MJ, Gomez-Hurtado N, Venkataraman R, Gibbs CE, Baudenbacher FJ, Gong S, Fishman GI, Boyle PM, Pfeifer K, Knollmann BC. Blackwell DJ, et al. Among authors: knollmann bc. JCI Insight. 2022 Feb 8;7(3):e151893. doi: 10.1172/jci.insight.151893. JCI Insight. 2022. PMID: 34990403 Free PMC article.
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.
Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC. Chopra N, et al. Among authors: knollmann bc, knollmann ritschel be. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7636-41. doi: 10.1073/pnas.0902919106. Epub 2009 Apr 21. Proc Natl Acad Sci U S A. 2009. PMID: 19383796 Free PMC article.
187 results