Yang C - Search Results

1

An innovative approach to the treatment of Gaucher disease and possibly other metabolic disorders of the brain.

Brady RO, Yang C, Zhuang Z. Brady RO, et al. Among authors: yang c. J Inherit Metab Dis. 2013 May;36(3):451-4. doi: 10.1007/s10545-012-9515-9. Epub 2012 Jul 20. J Inherit Metab Dis. 2013. PMID: 22814681 Free PMC article. Review.

2

Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.

Lu J, Chiang J, Iyer RR, Thompson E, Kaneski CR, Xu DS, Yang C, Chen M, Hodes RJ, Lonser RR, Brady RO, Zhuang Z. Lu J, et al. Among authors: yang c. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21665-70. doi: 10.1073/pnas.1014376107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098288 Free PMC article.

3

Missense mutations in the NF2 gene result in the quantitative loss of merlin protein and minimally affect protein intrinsic function.

Yang C, Asthagiri AR, Iyer RR, Lu J, Xu DS, Ksendzovsky A, Brady RO, Zhuang Z, Lonser RR. Yang C, et al. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4980-5. doi: 10.1073/pnas.1102198108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383154 Free PMC article.

4

Proteomic identification of glutamine synthetase as a differential marker for oligodendrogliomas and astrocytomas.

Zhuang Z, Qi M, Li J, Okamoto H, Xu DS, Iyer RR, Lu J, Yang C, Weil RJ, Vortmeyer A, Lonser RR. Zhuang Z, et al. Among authors: yang c. J Neurosurg. 2011 Oct;115(4):789-95. doi: 10.3171/2011.5.JNS11451. Epub 2011 Jun 17. J Neurosurg. 2011. PMID: 21682567 Free PMC article.

5

Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease.

Lu J, Yang C, Chen M, Ye DY, Lonser RR, Brady RO, Zhuang Z. Lu J, et al. Among authors: yang c. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21200-5. doi: 10.1073/pnas.1119181109. Epub 2011 Dec 12. Proc Natl Acad Sci U S A. 2011. PMID: 22160715 Free PMC article.

6

β-Catenin signaling initiates the activation of astrocytes and its dysregulation contributes to the pathogenesis of astrocytomas.

Yang C, Iyer RR, Yu AC, Yong RL, Park DM, Weil RJ, Ikejiri B, Brady RO, Lonser RR, Zhuang Z. Yang C, et al. Proc Natl Acad Sci U S A. 2012 May 1;109(18):6963-8. doi: 10.1073/pnas.1118754109. Epub 2012 Apr 13. Proc Natl Acad Sci U S A. 2012. PMID: 22505738 Free PMC article.

7

Neuronatin in a subset of glioblastoma multiforme tumor progenitor cells is associated with increased cell proliferation and shorter patient survival.

Xu DS, Yang C, Proescholdt M, Bründl E, Brawanski A, Fang X, Lee CS, Weil RJ, Zhuang Z, Lonser RR. Xu DS, et al. Among authors: yang c. PLoS One. 2012;7(5):e37811. doi: 10.1371/journal.pone.0037811. Epub 2012 May 18. PLoS One. 2012. PMID: 22624064 Free PMC article.

8

Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function.

Yang C, Matro JC, Huntoon KM, Ye DY, Huynh TT, Fliedner SM, Breza J, Zhuang Z, Pacak K. Yang C, et al. FASEB J. 2012 Nov;26(11):4506-16. doi: 10.1096/fj.12-210146. Epub 2012 Jul 26. FASEB J. 2012. PMID: 22835832 Free PMC article.

9

Somatic HIF2A gain-of-function mutations in paraganglioma with polycythemia.

Zhuang Z, Yang C, Lorenzo F, Merino M, Fojo T, Kebebew E, Popovic V, Stratakis CA, Prchal JT, Pacak K. Zhuang Z, et al. Among authors: yang c. N Engl J Med. 2012 Sep 6;367(10):922-30. doi: 10.1056/NEJMoa1205119. N Engl J Med. 2012. PMID: 22931260 Free PMC article.

10

CNTF receptor subunit α as a marker for glioma tumor-initiating cells and tumor grade: laboratory investigation.

Lu J, Ksendzovsky A, Yang C, Mehta GU, Yong RL, Weil RJ, Park DM, Mushlin HM, Fang X, Balgley BM, Lee DH, Lee CS, Lonser RR, Zhuang Z. Lu J, et al. Among authors: yang c. J Neurosurg. 2012 Dec;117(6):1022-1031. doi: 10.3171/2012.9.JNS1212. Epub 2012 Oct 12. J Neurosurg. 2012. PMID: 23061382 Free PMC article.

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