Ishikawa Y - Search Results

1

Pharmacological stimulation of type 5 adenylyl cyclase stabilizes heart rate under both microgravity and hypergravity induced by parabolic flight.

Bai Y, Tsunematsu T, Jiao Q, Ohnuki Y, Mototani Y, Shiozawa K, Jin M, Cai W, Jin HL, Fujita T, Ichikawa Y, Suita K, Kurotani R, Yokoyama U, Sato M, Iwatsubo K, Ishikawa Y, Okumura S. Bai Y, et al. Among authors: ishikawa y. J Pharmacol Sci. 2012;119(4):381-9. doi: 10.1254/jphs.12102fp. Epub 2012 Jul 31. J Pharmacol Sci. 2012. PMID: 22850613 Free article.

2

Isoform-specific regulation of adenylyl cyclase: a potential target in future pharmacotherapy.

Iwatsubo K, Tsunematsu T, Ishikawa Y. Iwatsubo K, et al. Among authors: ishikawa y. Expert Opin Ther Targets. 2003 Jun;7(3):441-51. doi: 10.1517/14728222.7.3.441. Expert Opin Ther Targets. 2003. PMID: 12783579 Review.

3

Drug therapy aimed at adenylyl cyclase to regulate cyclic nucleotide signaling.

Iwatsubo K, Okumura S, Ishikawa Y. Iwatsubo K, et al. Among authors: ishikawa y. Endocr Metab Immune Disord Drug Targets. 2006 Sep;6(3):239-47. doi: 10.2174/187153006778249994. Endocr Metab Immune Disord Drug Targets. 2006. PMID: 17017975 Review.

4

Type 5 adenylyl cyclase plays a major role in stabilizing heart rate in response to microgravity induced by parabolic flight.

Okumura S, Tsunematsu T, Bai Y, Jiao Q, Ono S, Suzuki S, Kurotani R, Sato M, Minamisawa S, Umemura S, Ishikawa Y. Okumura S, et al. Among authors: ishikawa y. J Appl Physiol (1985). 2008 Jul;105(1):173-9. doi: 10.1152/japplphysiol.01166.2007. Epub 2008 May 1. J Appl Physiol (1985). 2008. PMID: 18450980 Free PMC article.

5

New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: effects of targeted disruption of the type 5 adenylyl cyclase gene.

Okumura S, Suzuki S, Ishikawa Y. Okumura S, et al. Among authors: ishikawa y. J Pharmacol Sci. 2009 Mar;109(3):354-9. doi: 10.1254/jphs.08r26fm. Epub 2009 Mar 7. J Pharmacol Sci. 2009. PMID: 19270422 Free article. Review.

6

Coupling of β1-adrenergic receptor to type 5 adenylyl cyclase and its physiological relevance in cardiac myocytes.

Tsunematsu T, Okumura S, Mototani Y, Ohnuki Y, Jin H, Cai W, Suita K, Sato I, Umemura M, Yokoyama U, Sato M, Fujita T, Ishikawa Y. Tsunematsu T, et al. Among authors: ishikawa y. Biochem Biophys Res Commun. 2015 Mar 13;458(3):531-535. doi: 10.1016/j.bbrc.2015.01.149. Epub 2015 Feb 9. Biochem Biophys Res Commun. 2015. PMID: 25677623

7

Disruption of Epac1 protects the heart from adenylyl cyclase type 5-mediated cardiac dysfunction.

Cai W, Fujita T, Hidaka Y, Jin H, Suita K, Prajapati R, Liang C, Umemura M, Yokoyama U, Sato M, Okumura S, Ishikawa Y. Cai W, et al. Among authors: ishikawa y. Biochem Biophys Res Commun. 2016 Jun 17;475(1):1-7. doi: 10.1016/j.bbrc.2016.04.123. Epub 2016 Apr 24. Biochem Biophys Res Commun. 2016. PMID: 27117748

8

Vidarabine, an anti-herpesvirus agent, prevents catecholamine-induced arrhythmias without adverse effect on heart function in mice.

Suita K, Fujita T, Cai W, Hidaka Y, Jin H, Prajapati R, Umemura M, Yokoyama U, Sato M, Knollmann BC, Okumura S, Ishikawa Y. Suita K, et al. Among authors: ishikawa y. Pflugers Arch. 2018 Jun;470(6):923-935. doi: 10.1007/s00424-018-2121-4. Epub 2018 Feb 16. Pflugers Arch. 2018. PMID: 29453615

9

Motor dysfunction in type 5 adenylyl cyclase-null mice.

Iwamoto T, Okumura S, Iwatsubo K, Kawabe J, Ohtsu K, Sakai I, Hashimoto Y, Izumitani A, Sango K, Ajiki K, Toya Y, Umemura S, Goshima Y, Arai N, Vatner SF, Ishikawa Y. Iwamoto T, et al. Among authors: ishikawa y. J Biol Chem. 2003 May 9;278(19):16936-40. doi: 10.1074/jbc.C300075200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665504 Free article.

10

Disruption of type 5 adenylyl cyclase negates the developmental increase in Galphaolf expression in the striatum.

Iwamoto T, Iwatsubo K, Okumura S, Hashimoto Y, Tsunematsu T, Toya Y, Hervé D, Umemura S, Ishikawa Y. Iwamoto T, et al. Among authors: ishikawa y. FEBS Lett. 2004 Apr 23;564(1-2):153-6. doi: 10.1016/S0014-5793(04)00333-3. FEBS Lett. 2004. PMID: 15094058 Free article.

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