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Detection of ultra-rare mutations by next-generation sequencing.
Schmitt MW, Kennedy SR, Salk JJ, Fox EJ, Hiatt JB, Loeb LA. Schmitt MW, et al. Among authors: kennedy sr. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14508-13. doi: 10.1073/pnas.1208715109. Epub 2012 Aug 1. Proc Natl Acad Sci U S A. 2012. PMID: 22853953 Free PMC article.
Somatic mutations in aging, cancer and neurodegeneration.
Kennedy SR, Loeb LA, Herr AJ. Kennedy SR, et al. Mech Ageing Dev. 2012 Apr;133(4):118-26. doi: 10.1016/j.mad.2011.10.009. Epub 2011 Nov 3. Mech Ageing Dev. 2012. PMID: 22079405 Free PMC article. Review.
Detecting ultralow-frequency mutations by Duplex Sequencing.
Kennedy SR, Schmitt MW, Fox EJ, Kohrn BF, Salk JJ, Ahn EH, Prindle MJ, Kuong KJ, Shen JC, Risques RA, Loeb LA. Kennedy SR, et al. Nat Protoc. 2014 Nov;9(11):2586-606. doi: 10.1038/nprot.2014.170. Epub 2014 Oct 9. Nat Protoc. 2014. PMID: 25299156 Free PMC article.
Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS).
Nachmanson D, Lian S, Schmidt EK, Hipp MJ, Baker KT, Zhang Y, Tretiakova M, Loubet-Senear K, Kohrn BF, Salk JJ, Kennedy SR, Risques RA. Nachmanson D, et al. Among authors: kennedy sr. Genome Res. 2018 Oct;28(10):1589-1599. doi: 10.1101/gr.235291.118. Epub 2018 Sep 19. Genome Res. 2018. PMID: 30232196 Free PMC article.
Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes.
Lee MB, Dowsett IT, Carr DT, Wasko BM, Stanton SG, Chung MS, Ghodsian N, Bode A, Kiflezghi MG, Uppal PA, Grayden KA, Elala YC, Tang TT, Tran NHB, Tran THB, Diep AB, Hope M, Promislow DEL, Kennedy SR, Kaeberlein M, Herr AJ. Lee MB, et al. Among authors: kennedy sr. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3062-3071. doi: 10.1073/pnas.1815966116. Epub 2019 Feb 4. Proc Natl Acad Sci U S A. 2019. PMID: 30718408 Free PMC article.
87 results