Wang G - Search Results

1

Combining pharmacophore, docking and substructure search approaches to identify and optimize novel B-RafV600E inhibitors.

Xu Z, Yan G, Wang G, Li B, Zhu J, Sun P, Zhang X, Luo C, Wang H, Zhu W. Xu Z, et al. Among authors: wang h, wang g. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5428-37. doi: 10.1016/j.bmcl.2012.07.039. Epub 2012 Jul 17. Bioorg Med Chem Lett. 2012. PMID: 22858139

2

Dodoviscin a inhibits melanogenesis in mouse b16-f10 melanoma cells.

Yan G, Zhu J, Zhang L, Xu Z, Wang G, Zhu W, Hou A, Wang H. Yan G, et al. Among authors: wang h, wang g. Planta Med. 2013 Jul;79(11):933-8. doi: 10.1055/s-0032-1328649. Epub 2013 Jun 26. Planta Med. 2013. PMID: 23804039

3

Overman rearrangement and Pomeranz-Fritsch reaction for the synthesis of benzoazepinoisoquinolones to discover novel antitumor agents.

Li B, Wang G, Yang M, Xu Z, Zeng B, Wang H, Shen J, Chen K, Zhu W. Li B, et al. Among authors: wang h, wang g. Eur J Med Chem. 2013;70:677-84. doi: 10.1016/j.ejmech.2013.10.049. Epub 2013 Oct 25. Eur J Med Chem. 2013. PMID: 24215818

4

Aphadilactones A-D, four diterpenoid dimers with DGAT inhibitory and antimalarial activities from a Meliaceae plant.

Liu J, He XF, Wang GH, Merino EF, Yang SP, Zhu RX, Gan LS, Zhang H, Cassera MB, Wang HY, Kingston DG, Yue JM. Liu J, et al. Among authors: wang gh, wang hy. J Org Chem. 2014 Jan 17;79(2):599-607. doi: 10.1021/jo402340h. Epub 2013 Dec 23. J Org Chem. 2014. PMID: 24344740

5

Discovery of N-substituted 3-arylisoquinolone derivatives as antitumor agents originating from O-substituted 3-arylisoquinolines via [2,3] or [3,3] rearrangement.

Li B, Wang G, Xu Z, Zhang Y, Huang X, Zeng B, Chen K, Shi J, Wang H, Zhu W. Li B, et al. Among authors: wang h, wang g. Eur J Med Chem. 2014 Apr 22;77:204-10. doi: 10.1016/j.ejmech.2014.03.008. Epub 2014 Mar 6. Eur J Med Chem. 2014. PMID: 24637214

6

Inhibitory Effects of (2'R)-2',3'-dihydro-2'-(1-hydroxy-1-methylethyl)-2,6'-bibenzofuran-6,4'-diol on Mushroom Tyrosinase and Melanogenesis in B16-F10 Melanoma Cells.

Zhu JJ, Yan GR, Xu ZJ, Hu X, Wang GH, Wang T, Zhu WL, Hou AJ, Wang HY. Zhu JJ, et al. Phytother Res. 2015 Jul;29(7):1040-5. doi: 10.1002/ptr.5344. Epub 2015 Mar 31. Phytother Res. 2015. PMID: 25826437

7

Discovery of a low-systemic-exposure DGAT-1 inhibitor with a picolinoylpyrrolidine-2-carboxylic acid moiety.

Yan J, Wang G, Dang X, Guo B, Chen W, Wang T, Zeng L, Wang H, Hu Y. Yan J, et al. Among authors: wang h, wang g, wang t. Bioorg Med Chem. 2017 Sep 1;25(17):4701-4714. doi: 10.1016/j.bmc.2017.07.007. Epub 2017 Jul 14. Bioorg Med Chem. 2017. PMID: 28739155

8

DGAT1 inhibitors protect pancreatic β-cells from palmitic acid-induced apoptosis.

Huang JS, Guo BB, Wang GH, Zeng LM, Hu YH, Wang T, Wang HY. Huang JS, et al. Acta Pharmacol Sin. 2021 Feb;42(2):264-271. doi: 10.1038/s41401-020-0482-7. Epub 2020 Jul 31. Acta Pharmacol Sin. 2021. PMID: 32737468 Free PMC article.

9

Novel approaches to drug discovery for the treatment of type 2 diabetes.

Xu X, Wang G, Zhou T, Chen L, Chen J, Shen X. Xu X, et al. Among authors: wang g. Expert Opin Drug Discov. 2014 Sep;9(9):1047-58. doi: 10.1517/17460441.2014.941352. Epub 2014 Jul 23. Expert Opin Drug Discov. 2014. PMID: 25054271 Review.

10

Latanoprost effectively ameliorates glucose and lipid disorders in db/db and ob/ob mice.

Wang G, Xu X, Yao X, Zhu Z, Yu L, Chen L, Chen J, Shen X. Wang G, et al. Diabetologia. 2013 Dec;56(12):2702-12. doi: 10.1007/s00125-013-3032-8. Epub 2013 Aug 29. Diabetologia. 2013. PMID: 23989723

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