Yan G - Search Results

1

Combining pharmacophore, docking and substructure search approaches to identify and optimize novel B-RafV600E inhibitors.

Xu Z, Yan G, Wang G, Li B, Zhu J, Sun P, Zhang X, Luo C, Wang H, Zhu W. Xu Z, et al. Among authors: yan g. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5428-37. doi: 10.1016/j.bmcl.2012.07.039. Epub 2012 Jul 17. Bioorg Med Chem Lett. 2012. PMID: 22858139

2

Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening.

Cai H, Yan G, Zhang X, Gorbenko O, Wang H, Zhu W. Cai H, et al. Among authors: yan g. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3675-9. doi: 10.1016/j.bmcl.2010.04.095. Epub 2010 Apr 24. Bioorg Med Chem Lett. 2010. PMID: 20471252

3

[Progress of anti-tumor study based on BRAF].

Yan GR, Xu ZJ, Wang HY, Zhu WL. Yan GR, et al. Yao Xue Xue Bao. 2012 Dec;47(12):1567-74. Yao Xue Xue Bao. 2012. PMID: 23460959 Review. Chinese.

4

DC260126, a small-molecule antagonist of GPR40, improves insulin tolerance but not glucose tolerance in obese Zucker rats.

Zhang X, Yan G, Li Y, Zhu W, Wang H. Zhang X, et al. Among authors: yan g. Biomed Pharmacother. 2010 Nov;64(9):647-51. doi: 10.1016/j.biopha.2010.06.008. Biomed Pharmacother. 2010. PMID: 20888730

5

Novel fatty acid binding protein 4 (FABP4) inhibitors: virtual screening, synthesis and crystal structure determination.

Cai H, Liu Q, Gao D, Wang T, Chen T, Yan G, Chen K, Xu Y, Wang H, Li Y, Zhu W. Cai H, et al. Among authors: yan g. Eur J Med Chem. 2015 Jan 27;90:241-50. doi: 10.1016/j.ejmech.2014.11.020. Epub 2014 Nov 11. Eur J Med Chem. 2015. PMID: 25461324

6

Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice.

Cai HY, Wang T, Zhao JC, Sun P, Yan GR, Ding HP, Li YX, Wang HY, Zhu WL, Chen KX. Cai HY, et al. Acta Pharmacol Sin. 2013 Nov;34(11):1397-402. doi: 10.1038/aps.2013.97. Epub 2013 Sep 30. Acta Pharmacol Sin. 2013. PMID: 24077632 Free PMC article.

7

Inhibitory Effects of (2'R)-2',3'-dihydro-2'-(1-hydroxy-1-methylethyl)-2,6'-bibenzofuran-6,4'-diol on Mushroom Tyrosinase and Melanogenesis in B16-F10 Melanoma Cells.

Zhu JJ, Yan GR, Xu ZJ, Hu X, Wang GH, Wang T, Zhu WL, Hou AJ, Wang HY. Zhu JJ, et al. Phytother Res. 2015 Jul;29(7):1040-5. doi: 10.1002/ptr.5344. Epub 2015 Mar 31. Phytother Res. 2015. PMID: 25826437

8

Dodoviscin a inhibits melanogenesis in mouse b16-f10 melanoma cells.

Yan G, Zhu J, Zhang L, Xu Z, Wang G, Zhu W, Hou A, Wang H. Yan G, et al. Planta Med. 2013 Jul;79(11):933-8. doi: 10.1055/s-0032-1328649. Epub 2013 Jun 26. Planta Med. 2013. PMID: 23804039

9

Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight gain, hyperlipidemia, and hepatic steatosis in db/db mice.

Zhang XD, Yan JW, Yan GR, Sun XY, Ji J, Li YM, Hu YH, Wang HY. Zhang XD, et al. Acta Pharmacol Sin. 2010 Nov;31(11):1470-7. doi: 10.1038/aps.2010.104. Acta Pharmacol Sin. 2010. PMID: 21052084 Free PMC article.

10

Sildenafil promotes adipogenesis through a PKG pathway.

Zhang X, Ji J, Yan G, Wu J, Sun X, Shen J, Jiang H, Wang H. Zhang X, et al. Among authors: yan g. Biochem Biophys Res Commun. 2010 Jun 11;396(4):1054-9. doi: 10.1016/j.bbrc.2010.05.064. Epub 2010 May 21. Biochem Biophys Res Commun. 2010. PMID: 20471953

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