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BRCA1 ubiquitinates RPB8 in response to DNA damage.
Wu W, Nishikawa H, Hayami R, Sato K, Honda A, Aratani S, Nakajima T, Fukuda M, Ohta T. Wu W, et al. Among authors: sato k. Cancer Res. 2007 Feb 1;67(3):951-8. doi: 10.1158/0008-5472.CAN-06-3187. Cancer Res. 2007. PMID: 17283126
HERC2 is an E3 ligase that targets BRCA1 for degradation.
Wu W, Sato K, Koike A, Nishikawa H, Koizumi H, Venkitaraman AR, Ohta T. Wu W, et al. Among authors: sato k. Cancer Res. 2010 Aug 1;70(15):6384-92. doi: 10.1158/0008-5472.CAN-10-1304. Epub 2010 Jul 14. Cancer Res. 2010. PMID: 20631078
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