Chambers JE - Search Results

1

ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load.

Chambers JE, Petrova K, Tomba G, Vendruscolo M, Ron D. Chambers JE, et al. J Cell Biol. 2012 Aug 6;198(3):371-85. doi: 10.1083/jcb.201202005. J Cell Biol. 2012. PMID: 22869598 Free PMC article.

2

Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker.

Preissler S, Chambers JE, Crespillo-Casado A, Avezov E, Miranda E, Perez J, Hendershot LM, Harding HP, Ron D. Preissler S, et al. Among authors: chambers je. Elife. 2015 Oct 16;4:e08961. doi: 10.7554/eLife.08961. Elife. 2015. PMID: 26473973 Free PMC article.

3

Pharmacological targeting of endoplasmic reticulum stress in disease.

Marciniak SJ, Chambers JE, Ron D. Marciniak SJ, et al. Among authors: chambers je. Nat Rev Drug Discov. 2022 Feb;21(2):115-140. doi: 10.1038/s41573-021-00320-3. Epub 2021 Oct 26. Nat Rev Drug Discov. 2022. PMID: 34702991 Review.

4

Single particle trajectories reveal active endoplasmic reticulum luminal flow.

Holcman D, Parutto P, Chambers JE, Fantham M, Young LJ, Marciniak SJ, Kaminski CF, Ron D, Avezov E. Holcman D, et al. Among authors: chambers je. Nat Cell Biol. 2018 Oct;20(10):1118-1125. doi: 10.1038/s41556-018-0192-2. Epub 2018 Sep 17. Nat Cell Biol. 2018. PMID: 30224760 Free PMC article.

5

Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 2. Protein misfolding and ER stress.

Chambers JE, Marciniak SJ. Chambers JE, et al. Am J Physiol Cell Physiol. 2014 Oct 15;307(8):C657-70. doi: 10.1152/ajpcell.00183.2014. Am J Physiol Cell Physiol. 2014. PMID: 24944205 Free article.

6

PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz.

Crespillo-Casado A, Chambers JE, Fischer PM, Marciniak SJ, Ron D. Crespillo-Casado A, et al. Among authors: chambers je. Elife. 2017 Apr 27;6:e26109. doi: 10.7554/eLife.26109. Elife. 2017. PMID: 28447936 Free PMC article.

7

Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation.

Chambers JE, Dalton LE, Clarke HJ, Malzer E, Dominicus CS, Patel V, Moorhead G, Ron D, Marciniak SJ. Chambers JE, et al. Elife. 2015 Mar 16;4:e04872. doi: 10.7554/eLife.04872. Elife. 2015. PMID: 25774599 Free PMC article.

8

Measuring the effects of α₁ -antitrypsin polymerisation on the structure and biophysical properties of the endoplasmic reticulum.

Chambers JE, Dickens JA, Marciniak SJ. Chambers JE, et al. Biol Cell. 2018 Nov;110(11):249-255. doi: 10.1111/boc.201800023. Epub 2018 Sep 10. Biol Cell. 2018. PMID: 30129166 Review.

9

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.

van Galen P, Kreso A, Mbong N, Kent DG, Fitzmaurice T, Chambers JE, Xie S, Laurenti E, Hermans K, Eppert K, Marciniak SJ, Goodall JC, Green AR, Wouters BG, Wienholds E, Dick JE. van Galen P, et al. Among authors: chambers je. Nature. 2014 Jun 12;510(7504):268-72. doi: 10.1038/nature13228. Epub 2014 Apr 28. Nature. 2014. PMID: 24776803

10

Endoplasmic reticulum stress in malignancy.

Clarke HJ, Chambers JE, Liniker E, Marciniak SJ. Clarke HJ, et al. Among authors: chambers je. Cancer Cell. 2014 May 12;25(5):563-73. doi: 10.1016/j.ccr.2014.03.015. Cancer Cell. 2014. PMID: 24823636 Free article. Review.

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