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Page 1
Differences in FKBP51 regulation following chronic social defeat stress correlate with individual stress sensitivity: influence of paroxetine treatment.
Wagner KV, Marinescu D, Hartmann J, Wang XD, Labermaier C, Scharf SH, Liebl C, Uhr M, Holsboer F, Müller MB, Schmidt MV. Wagner KV, et al. Among authors: holsboer f. Neuropsychopharmacology. 2012 Dec;37(13):2797-808. doi: 10.1038/npp.2012.150. Epub 2012 Aug 8. Neuropsychopharmacology. 2012. PMID: 22871917 Free PMC article.
Reduction of hypothalamic vasopressinergic hyperdrive contributes to clinically relevant behavioral and neuroendocrine effects of chronic paroxetine treatment in a psychopathological rat model.
Keck ME, Welt T, Müller MB, Uhr M, Ohl F, Wigger A, Toschi N, Holsboer F, Landgraf R. Keck ME, et al. Among authors: holsboer f. Neuropsychopharmacology. 2003 Feb;28(2):235-43. doi: 10.1038/sj.npp.1300040. Epub 2002 Jul 25. Neuropsychopharmacology. 2003. PMID: 12589376
The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress.
Hartmann J, Wagner KV, Liebl C, Scharf SH, Wang XD, Wolf M, Hausch F, Rein T, Schmidt U, Touma C, Cheung-Flynn J, Cox MB, Smith DF, Holsboer F, Müller MB, Schmidt MV. Hartmann J, et al. Among authors: holsboer f. Neuropharmacology. 2012 Jan;62(1):332-9. doi: 10.1016/j.neuropharm.2011.07.041. Epub 2011 Aug 4. Neuropharmacology. 2012. PMID: 21839098
The prospect of FKBP51 as a drug target.
Schmidt MV, Paez-Pereda M, Holsboer F, Hausch F. Schmidt MV, et al. Among authors: holsboer f. ChemMedChem. 2012 Aug;7(8):1351-9. doi: 10.1002/cmdc.201200137. Epub 2012 May 13. ChemMedChem. 2012. PMID: 22581765
Fkbp52 heterozygosity alters behavioral, endocrine and neurogenetic parameters under basal and chronic stress conditions in mice.
Hartmann J, Wagner KV, Dedic N, Marinescu D, Scharf SH, Wang XD, Deussing JM, Hausch F, Rein T, Schmidt U, Holsboer F, Müller MB, Schmidt MV. Hartmann J, et al. Among authors: holsboer f. Psychoneuroendocrinology. 2012 Dec;37(12):2009-21. doi: 10.1016/j.psyneuen.2012.04.017. Epub 2012 May 27. Psychoneuroendocrinology. 2012. PMID: 22641006
Homer1 mediates acute stress-induced cognitive deficits in the dorsal hippocampus.
Wagner KV, Hartmann J, Mangold K, Wang XD, Labermaier C, Liebl C, Wolf M, Gassen NC, Holsboer F, Rein T, Müller MB, Schmidt MV. Wagner KV, et al. Among authors: holsboer f. J Neurosci. 2013 Feb 27;33(9):3857-64. doi: 10.1523/JNEUROSCI.4333-12.2013. J Neurosci. 2013. PMID: 23447597 Free PMC article.
Evidence supporting the match/mismatch hypothesis of psychiatric disorders.
Santarelli S, Lesuis SL, Wang XD, Wagner KV, Hartmann J, Labermaier C, Scharf SH, Müller MB, Holsboer F, Schmidt MV. Santarelli S, et al. Among authors: holsboer f. Eur Neuropsychopharmacol. 2014 Jun;24(6):907-18. doi: 10.1016/j.euroneuro.2014.02.002. Epub 2014 Feb 15. Eur Neuropsychopharmacol. 2014. PMID: 24589292
Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans.
Gassen NC, Hartmann J, Zschocke J, Stepan J, Hafner K, Zellner A, Kirmeier T, Kollmannsberger L, Wagner KV, Dedic N, Balsevich G, Deussing JM, Kloiber S, Lucae S, Holsboer F, Eder M, Uhr M, Ising M, Schmidt MV, Rein T. Gassen NC, et al. Among authors: holsboer f. PLoS Med. 2014 Nov 11;11(11):e1001755. doi: 10.1371/journal.pmed.1001755. eCollection 2014 Nov. PLoS Med. 2014. PMID: 25386878 Free PMC article.
Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties.
Hartmann J, Wagner KV, Gaali S, Kirschner A, Kozany C, Rühter G, Dedic N, Häusl AS, Hoeijmakers L, Westerholz S, Namendorf C, Gerlach T, Uhr M, Chen A, Deussing JM, Holsboer F, Hausch F, Schmidt MV. Hartmann J, et al. Among authors: holsboer f. J Neurosci. 2015 Jun 17;35(24):9007-16. doi: 10.1523/JNEUROSCI.4024-14.2015. J Neurosci. 2015. PMID: 26085626 Free PMC article.
832 results