Lim WA - Search Results

1

Conformational control of the Ste5 scaffold protein insulates against MAP kinase misactivation.

Zalatan JG, Coyle SM, Rajan S, Sidhu SS, Lim WA. Zalatan JG, et al. Among authors: lim wa. Science. 2012 Sep 7;337(6099):1218-22. doi: 10.1126/science.1220683. Epub 2012 Aug 9. Science. 2012. PMID: 22878499 Free PMC article.

2

Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms.

Park SH, Zarrinpar A, Lim WA. Park SH, et al. Among authors: lim wa. Science. 2003 Feb 14;299(5609):1061-4. doi: 10.1126/science.1076979. Epub 2003 Jan 2. Science. 2003. PMID: 12511654

3

Reprogramming control of an allosteric signaling switch through modular recombination.

Dueber JE, Yeh BJ, Chak K, Lim WA. Dueber JE, et al. Among authors: lim wa. Science. 2003 Sep 26;301(5641):1904-8. doi: 10.1126/science.1085945. Science. 2003. PMID: 14512628

4

Optimization of specificity in a cellular protein interaction network by negative selection.

Zarrinpar A, Park SH, Lim WA. Zarrinpar A, et al. Among authors: lim wa. Nature. 2003 Dec 11;426(6967):676-80. doi: 10.1038/nature02178. Nature. 2003. PMID: 14668868

5

Sho1 and Pbs2 act as coscaffolds linking components in the yeast high osmolarity MAP kinase pathway.

Zarrinpar A, Bhattacharyya RP, Nittler MP, Lim WA. Zarrinpar A, et al. Among authors: lim wa. Mol Cell. 2004 Jun 18;14(6):825-32. doi: 10.1016/j.molcel.2004.06.011. Mol Cell. 2004. PMID: 15200959 Free article.

6

The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network.

Reményi A, Good MC, Bhattacharyya RP, Lim WA. Reményi A, et al. Among authors: lim wa. Mol Cell. 2005 Dec 22;20(6):951-62. doi: 10.1016/j.molcel.2005.10.030. Mol Cell. 2005. PMID: 16364919 Free article.

7

The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.

Bhattacharyya RP, Reményi A, Good MC, Bashor CJ, Falick AM, Lim WA. Bhattacharyya RP, et al. Among authors: lim wa. Science. 2006 Feb 10;311(5762):822-6. doi: 10.1126/science.1120941. Epub 2006 Jan 19. Science. 2006. PMID: 16424299

8

Docking interactions in protein kinase and phosphatase networks.

Reményi A, Good MC, Lim WA. Reményi A, et al. Among authors: lim wa. Curr Opin Struct Biol. 2006 Dec;16(6):676-85. doi: 10.1016/j.sbi.2006.10.008. Epub 2006 Oct 31. Curr Opin Struct Biol. 2006. PMID: 17079133 Review.

9

Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics.

Bashor CJ, Helman NC, Yan S, Lim WA. Bashor CJ, et al. Among authors: lim wa. Science. 2008 Mar 14;319(5869):1539-43. doi: 10.1126/science.1151153. Science. 2008. PMID: 18339942

10

The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation.

Good M, Tang G, Singleton J, Reményi A, Lim WA. Good M, et al. Among authors: lim wa. Cell. 2009 Mar 20;136(6):1085-97. doi: 10.1016/j.cell.2009.01.049. Cell. 2009. PMID: 19303851 Free PMC article.

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