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beta-arrestin-biased agonism at the beta2-adrenergic receptor.
Drake MT, Violin JD, Whalen EJ, Wisler JW, Shenoy SK, Lefkowitz RJ. Drake MT, et al. Among authors: violin jd. J Biol Chem. 2008 Feb 29;283(9):5669-76. doi: 10.1074/jbc.M708118200. Epub 2007 Dec 17. J Biol Chem. 2008. PMID: 18086673 Free article.
Heart failure therapeutics on the basis of a biased ligand of the angiotensin-2 type 1 receptor. Rationale and design of the BLAST-AHF study (Biased Ligand of the Angiotensin Receptor Study in Acute Heart Failure).
Felker GM, Butler J, Collins SP, Cotter G, Davison BA, Ezekowitz JA, Filippatos G, Levy PD, Metra M, Ponikowski P, Soergel DG, Teerlink JR, Violin JD, Voors AA, Pang PS. Felker GM, et al. Among authors: violin jd. JACC Heart Fail. 2015 Mar;3(3):193-201. doi: 10.1016/j.jchf.2014.09.008. Epub 2015 Jan 28. JACC Heart Fail. 2015. PMID: 25650371 Free article. Review.
The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium.
Monasky MM, Taglieri DM, Henze M, Warren CM, Utter MS, Soergel DG, Violin JD, Solaro RJ. Monasky MM, et al. Among authors: violin jd. Am J Physiol Heart Circ Physiol. 2013 Sep 15;305(6):H856-66. doi: 10.1152/ajpheart.00327.2013. Epub 2013 Jul 19. Am J Physiol Heart Circ Physiol. 2013. PMID: 23873795 Free PMC article.
47 results