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Synthesis and evaluation of 2-pyridylbenzothiazole, 2-pyridylbenzoxazole and 2-pyridylbenzofuran derivatives as 11C-PET imaging agents for beta-amyloid plaques.
Swahn BM, Wensbo D, Sandell J, Sohn D, Slivo C, Pyring D, Malmström J, Arzel E, Vallin M, Bergh M, Jeppsson F, Johnson AE, Juréus A, Neelissen J, Svensson S. Swahn BM, et al. Among authors: malmstrom j. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1976-80. doi: 10.1016/j.bmcl.2010.01.105. Epub 2010 Jan 25. Bioorg Med Chem Lett. 2010. PMID: 20153963
Core refinement toward permeable β-secretase (BACE-1) inhibitors with low hERG activity.
Ginman T, Viklund J, Malmström J, Blid J, Emond R, Forsblom R, Johansson A, Kers A, Lake F, Sehgelmeble F, Sterky KJ, Bergh M, Lindgren A, Johansson P, Jeppsson F, Fälting J, Gravenfors Y, Rahm F. Ginman T, et al. Among authors: malmstrom j. J Med Chem. 2013 Jun 13;56(11):4181-205. doi: 10.1021/jm3011349. Epub 2013 May 20. J Med Chem. 2013. PMID: 23126626
Structure-activity relationship of thiopyrimidines as mGluR5 antagonists.
Hammerland LG, Johansson M, Malmström J, Mattsson JP, Minidis AB, Nilsson K, Peterson A, Wensbo D, Wållberg A, Osterlund K. Hammerland LG, et al. Among authors: malmstrom j. Bioorg Med Chem Lett. 2006 May 1;16(9):2467-9. doi: 10.1016/j.bmcl.2006.01.100. Epub 2006 Feb 14. Bioorg Med Chem Lett. 2006. PMID: 16481165
Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system.
Selvaraju K, Mofers A, Pellegrini P, Salomonsson J, Ahlner A, Morad V, Hillert EK, Espinosa B, Arnér ESJ, Jensen L, Malmström J, Turkina MV, D'Arcy P, Walters MA, Sunnerhagen M, Linder S. Selvaraju K, et al. Among authors: malmstrom j. Sci Rep. 2019 Jul 8;9(1):9841. doi: 10.1038/s41598-019-46168-x. Sci Rep. 2019. PMID: 31285509 Free PMC article.
252 results