Liu Y - Search Results

1

Identification and synthesis of substituted pyrrolo[2,3-d]pyrimidines as novel firefly luciferase inhibitors.

Liu Y, Fang J, Cai H, Xiao F, Ding K, Hu Y. Liu Y, et al. Bioorg Med Chem. 2012 Sep 15;20(18):5473-82. doi: 10.1016/j.bmc.2012.07.035. Epub 2012 Jul 28. Bioorg Med Chem. 2012. PMID: 22898255

2

Design and synthesis of novel benzo[d]oxazol-2(3H)-one derivatives bearing 7-substituted-4-enthoxyquinoline moieties as c-Met kinase inhibitors.

Lu D, Shen A, Liu Y, Peng X, Xing W, Ai J, Geng M, Hu Y. Lu D, et al. Among authors: liu y. Eur J Med Chem. 2016 Jun 10;115:191-200. doi: 10.1016/j.ejmech.2016.03.027. Epub 2016 Mar 12. Eur J Med Chem. 2016. PMID: 27017548

3

Enhancing the cellular anti-proliferation activity of pyridazinones as c-met inhibitors using docking analysis.

Xing W, Ai J, Jin S, Shi Z, Peng X, Wang L, Ji Y, Lu D, Liu Y, Geng M, Hu Y. Xing W, et al. Among authors: liu y. Eur J Med Chem. 2015 May 5;95:302-12. doi: 10.1016/j.ejmech.2015.03.041. Epub 2015 Mar 21. Eur J Med Chem. 2015. PMID: 25827399

4

Pyridazinone derivatives displaying highly potent and selective inhibitory activities against c-Met tyrosine kinase.

Liu Y, Jin S, Peng X, Lu D, Zeng L, Sun Y, Ai J, Geng M, Hu Y. Liu Y, et al. Eur J Med Chem. 2016 Jan 27;108:322-333. doi: 10.1016/j.ejmech.2015.11.042. Epub 2015 Nov 30. Eur J Med Chem. 2016. PMID: 26698536

5

Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors.

Liu Y, Peng X, Guan X, Lu D, Xi Y, Jin S, Chen H, Zeng L, Ai J, Geng M, Hu Y. Liu Y, et al. Eur J Med Chem. 2017 Jan 27;126:122-132. doi: 10.1016/j.ejmech.2016.10.003. Epub 2016 Oct 4. Eur J Med Chem. 2017. PMID: 27750146

6

Base-promoted one-pot tandem reaction of 3-(1-alkynyl)chromones under microwave irradiation to functionalized amino-substituted xanthones.

Liu Y, Huang L, Xie F, Hu Y. Liu Y, et al. J Org Chem. 2010 Sep 17;75(18):6304-7. doi: 10.1021/jo1013614. J Org Chem. 2010. PMID: 20738144

7

Synthesis of novel functional polycyclic chromones through Michael addition and double cyclizations.

Liu Y, Huang L, Xie F, Chen X, Hu Y. Liu Y, et al. Org Biomol Chem. 2011 Apr 21;9(8):2680-4. doi: 10.1039/c0ob01000f. Epub 2011 Mar 2. Org Biomol Chem. 2011. PMID: 21369579

8

A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-κB signaling and improves survival in mouse models of sepsis.

Fang JP, Liu Y, Li J, Liao WF, Hu YH, Ding K. Fang JP, et al. Among authors: liu y. Acta Pharmacol Sin. 2012 Sep;33(9):1204-16. doi: 10.1038/aps.2012.56. Epub 2012 Jun 11. Acta Pharmacol Sin. 2012. PMID: 22684031 Free PMC article.

9

An organic molecule modulated chemoselective cyclization of alkynyl nitriles tethered to 2-alkyl substituted chromones with multireactive sites.

Huang L, Liu Y, Xie F, Hu Y. Huang L, et al. Among authors: liu y. Org Lett. 2012 Dec 21;14(24):6122-5. doi: 10.1021/ol302964x. Epub 2012 Dec 4. Org Lett. 2012. PMID: 23210678

10

Microwave assisted tandem Heck-Sonogashira reactions of N,N-di-Boc-protected 6-amino-5-iodo-2-methyl pyrimidin-4-ol in an efficient approach to functionalized pyrido[2,3-d]pyrimidines.

Liu Y, Jin S, Wang Z, Song L, Hu Y. Liu Y, et al. Org Lett. 2014 Jul 3;16(13):3524-7. doi: 10.1021/ol501459e. Epub 2014 Jun 23. Org Lett. 2014. PMID: 24956126

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