Buckner FS - Search Results

1

Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection.

Koh CY, Kim JE, Shibata S, Ranade RM, Yu M, Liu J, Gillespie JR, Buckner FS, Verlinde CL, Fan E, Hol WG. Koh CY, et al. Among authors: buckner fs. Structure. 2012 Oct 10;20(10):1681-91. doi: 10.1016/j.str.2012.07.011. Epub 2012 Aug 16. Structure. 2012. PMID: 22902861 Free PMC article.

2

Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase.

Buckner FS, Verlinde CL, La Flamme AC, Van Voorhis WC. Buckner FS, et al. Antimicrob Agents Chemother. 1996 Nov;40(11):2592-7. doi: 10.1128/AAC.40.11.2592. Antimicrob Agents Chemother. 1996. PMID: 8913471 Free PMC article.

3

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.

Aronov AM, Suresh S, Buckner FS, Van Voorhis WC, Verlinde CL, Opperdoes FR, Hol WG, Gelb MH. Aronov AM, et al. Among authors: buckner fs. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4273-8. doi: 10.1073/pnas.96.8.4273. Proc Natl Acad Sci U S A. 1999. PMID: 10200252 Free PMC article.

4

Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.

Bressi JC, Choe J, Hough MT, Buckner FS, Van Voorhis WC, Verlinde CL, Hol WG, Gelb MH. Bressi JC, et al. Among authors: buckner fs. J Med Chem. 2000 Nov 2;43(22):4135-50. doi: 10.1021/jm000287a. J Med Chem. 2000. PMID: 11063610

5

Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design.

Bressi JC, Verlinde CL, Aronov AM, Shaw ML, Shin SS, Nguyen LN, Suresh S, Buckner FS, Van Voorhis WC, Kuntz ID, Hol WG, Gelb MH. Bressi JC, et al. Among authors: buckner fs. J Med Chem. 2001 Jun 21;44(13):2080-93. doi: 10.1021/jm000472o. J Med Chem. 2001. PMID: 11405646 Free PMC article.

6

Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase.

Buckner FS, Joubert BM, Boyle SM, Eastman RT, Verlinde CL, Matsuda SP. Buckner FS, et al. Mol Biochem Parasitol. 2003 Dec;132(2):75-81. doi: 10.1016/j.molbiopara.2003.07.004. Mol Biochem Parasitol. 2003. PMID: 14599667

7

The protein farnesyltransferase inhibitor Tipifarnib as a new lead for the development of drugs against Chagas disease.

Hucke O, Gelb MH, Verlinde CL, Buckner FS. Hucke O, et al. Among authors: buckner fs. J Med Chem. 2005 Aug 25;48(17):5415-8. doi: 10.1021/jm050441z. J Med Chem. 2005. PMID: 16107140 Free PMC article.

8

Upregulation of sterol C14-demethylase expression in Trypanosoma cruzi treated with sterol biosynthesis inhibitors.

Hankins EG, Gillespie JR, Aikenhead K, Buckner FS. Hankins EG, et al. Among authors: buckner fs. Mol Biochem Parasitol. 2005 Nov;144(1):68-75. doi: 10.1016/j.molbiopara.2005.08.002. Mol Biochem Parasitol. 2005. PMID: 16165233

9

Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily.

Caruthers J, Zucker F, Worthey E, Myler PJ, Buckner F, Van Voorhuis W, Mehlin C, Boni E, Feist T, Luft J, Gulde S, Lauricella A, Kaluzhniy O, Anderson L, Le Trong I, Holmes MA, Earnest T, Soltis M, Hodgson KO, Hol WG, Merritt EA. Caruthers J, et al. Protein Sci. 2005 Nov;14(11):2887-94. doi: 10.1110/ps.051783005. Epub 2005 Sep 30. Protein Sci. 2005. PMID: 16199669 Free PMC article.

10

Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum.

Caruthers J, Bosch J, Buckner F, Van Voorhis W, Myler P, Worthey E, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Kalyuzhniy O, Anderson L, Zucker F, Soltis M, Hol WG. Caruthers J, et al. Proteins. 2006 Feb 1;62(2):338-42. doi: 10.1002/prot.20764. Proteins. 2006. PMID: 16304640

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