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E2F8 is essential for polyploidization in mammalian cells.
Pandit SK, Westendorp B, Nantasanti S, van Liere E, Tooten PC, Cornelissen PW, Toussaint MJ, Lamers WH, de Bruin A. Pandit SK, et al. Among authors: cornelissen pw. Nat Cell Biol. 2012 Nov;14(11):1181-91. doi: 10.1038/ncb2585. Epub 2012 Oct 14. Nat Cell Biol. 2012. PMID: 23064264