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Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.
Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, Martins RN. Bharadwaj PR, et al. Among authors: gupta v. J Alzheimers Dis. 2012;32(4):949-67. doi: 10.3233/JAD-2012-120178. J Alzheimers Dis. 2012. PMID: 22903131 Free PMC article.
Plasma amyloid-beta as a biomarker in Alzheimer's disease: the AIBL study of aging.
Lui JK, Laws SM, Li QX, Villemagne VL, Ames D, Brown B, Bush AI, De Ruyck K, Dromey J, Ellis KA, Faux NG, Foster J, Fowler C, Gupta V, Hudson P, Laughton K, Masters CL, Pertile K, Rembach A, Rimajova M, Rodrigues M, Rowe CC, Rumble R, Szoeke C, Taddei K, Taddei T, Trounson B, Ward V, Martins RN, AIBL Research Group. Lui JK, et al. Among authors: gupta v. J Alzheimers Dis. 2010;20(4):1233-42. doi: 10.3233/JAD-2010-090249. J Alzheimers Dis. 2010. PMID: 20413897
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.
Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Fraser P, Westaway D, St George-Hyslop PH, Szabo P, Relkin NR, Buxbaum JD, Glabe CG, Protter AA, Martins RN, Ehrlich ME, Petsko GA, Yue Z, Gandy S. Steele JW, et al. Among authors: gupta v. Mol Psychiatry. 2013 Aug;18(8):889-97. doi: 10.1038/mp.2012.106. Epub 2012 Jul 31. Mol Psychiatry. 2013. PMID: 22850627 Free PMC article.
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.
Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Protter AA, Martins RN, Ehrlich ME, Yue Z, Petsko GA, Gandy S. Steele JW, et al. Among authors: gupta v. Mol Psychiatry. 2013 Aug;18(8):882-8. doi: 10.1038/mp.2012.115. Epub 2012 Aug 7. Mol Psychiatry. 2013. PMID: 22869031 Free PMC article.
A blood-based predictor for neocortical Aβ burden in Alzheimer's disease: results from the AIBL study.
Burnham SC, Faux NG, Wilson W, Laws SM, Ames D, Bedo J, Bush AI, Doecke JD, Ellis KA, Head R, Jones G, Kiiveri H, Martins RN, Rembach A, Rowe CC, Salvado O, Macaulay SL, Masters CL, Villemagne VL; Alzheimer’s Disease Neuroimaging Initiative; Australian Imaging, Biomarkers and Lifestyle Study Research Group. Burnham SC, et al. Mol Psychiatry. 2014 Apr;19(4):519-26. doi: 10.1038/mp.2013.40. Epub 2013 Apr 30. Mol Psychiatry. 2014. PMID: 23628985
Multiplex biomarkers in blood.
Gupta VB, Sundaram R, Martins RN. Gupta VB, et al. Alzheimers Res Ther. 2013 Jun 25;5(3):31. doi: 10.1186/alzrt185. eCollection 2013. Alzheimers Res Ther. 2013. PMID: 23795953 Free PMC article. Review.
Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research.
O'Bryant SE, Gupta V, Henriksen K, Edwards M, Jeromin A, Lista S, Bazenet C, Soares H, Lovestone S, Hampel H, Montine T, Blennow K, Foroud T, Carrillo M, Graff-Radford N, Laske C, Breteler M, Shaw L, Trojanowski JQ, Schupf N, Rissman RA, Fagan AM, Oberoi P, Umek R, Weiner MW, Grammas P, Posner H, Martins R; STAR-B and BBBIG working groups. O'Bryant SE, et al. Among authors: gupta v. Alzheimers Dement. 2015 May;11(5):549-60. doi: 10.1016/j.jalz.2014.08.099. Epub 2014 Oct 1. Alzheimers Dement. 2015. PMID: 25282381 Free PMC article. Review.
Cerebral amyloid-β accumulation and deposition following traumatic brain injury--A narrative review and meta-analysis of animal studies.
Bird SM, Sohrabi HR, Sutton TA, Weinborn M, Rainey-Smith SR, Brown B, Patterson L, Taddei K, Gupta V, Carruthers M, Lenzo N, Knuckey N, Bucks RS, Verdile G, Martins RN. Bird SM, et al. Among authors: gupta v. Neurosci Biobehav Rev. 2016 May;64:215-28. doi: 10.1016/j.neubiorev.2016.01.004. Epub 2016 Feb 17. Neurosci Biobehav Rev. 2016. PMID: 26899257 Review.
Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges.
O'Bryant SE, Lista S, Rissman RA, Edwards M, Zhang F, Hall J, Zetterberg H, Lovestone S, Gupta V, Graff-Radford N, Martins R, Jeromin A, Waring S, Oh E, Kling M, Baker LD, Hampel H. O'Bryant SE, et al. Among authors: gupta v. Alzheimers Dement (Amst). 2015 Dec 29;3:27-34. doi: 10.1016/j.dadm.2015.12.003. eCollection 2016. Alzheimers Dement (Amst). 2015. PMID: 27019866 Free PMC article.
Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging.
Gupta VB, Doecke JD, Hone E, Pedrini S, Laws SM, Thambisetty M, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Macaulay SL, Rembach A, Rainey-Smith SR, Martins RN; AIBL Research Group. Gupta VB, et al. Alzheimers Dement (Amst). 2015 Dec 22;3:18-26. doi: 10.1016/j.dadm.2015.12.001. eCollection 2016. Alzheimers Dement (Amst). 2015. PMID: 27239546 Free PMC article.
7,927 results