Medema RH - Search Results

1

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.

Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Reinhardt HC, Benzing T. Höpker K, et al. Among authors: medema rh. EMBO J. 2012 Oct 17;31(20):3961-75. doi: 10.1038/emboj.2012.236. Epub 2012 Aug 21. EMBO J. 2012. PMID: 22909821 Free PMC article.

2

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery.

Macůrek L, Lindqvist A, Lim D, Lampson MA, Klompmaker R, Freire R, Clouin C, Taylor SS, Yaffe MB, Medema RH. Macůrek L, et al. Among authors: medema rh. Nature. 2008 Sep 4;455(7209):119-23. doi: 10.1038/nature07185. Epub 2008 Jul 9. Nature. 2008. PMID: 18615013

3

Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins.

Bouchard C, Marquardt J, Brás A, Medema RH, Eilers M. Bouchard C, et al. Among authors: medema rh. EMBO J. 2004 Jul 21;23(14):2830-40. doi: 10.1038/sj.emboj.7600279. Epub 2004 Jul 8. EMBO J. 2004. PMID: 15241468 Free PMC article.

4

Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1.

van Leuken R, Clijsters L, van Zon W, Lim D, Yao X, Wolthuis RM, Yaffe MB, Medema RH, van Vugt MA. van Leuken R, et al. Among authors: medema rh. PLoS One. 2009;4(4):e5282. doi: 10.1371/journal.pone.0005282. Epub 2009 Apr 23. PLoS One. 2009. PMID: 19390576 Free PMC article.

5

Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression.

Lindqvist A, de Bruijn M, Macurek L, Brás A, Mensinga A, Bruinsma W, Voets O, Kranenburg O, Medema RH. Lindqvist A, et al. Among authors: medema rh. EMBO J. 2009 Oct 21;28(20):3196-206. doi: 10.1038/emboj.2009.246. Epub 2009 Aug 27. EMBO J. 2009. PMID: 19713933 Free PMC article.

6

Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1.

Alvarez-Fernández M, Halim VA, Krenning L, Aprelia M, Mohammed S, Heck AJ, Medema RH. Alvarez-Fernández M, et al. Among authors: medema rh. EMBO Rep. 2010 Jun;11(6):452-8. doi: 10.1038/embor.2010.46. Epub 2010 Apr 9. EMBO Rep. 2010. PMID: 20379221 Free PMC article.

7

Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest.

Bruinsma W, van den Berg J, Aprelia M, Medema RH. Bruinsma W, et al. Among authors: medema rh. EMBO Rep. 2016 May;17(5):659-70. doi: 10.15252/embr.201540767. Epub 2016 Mar 1. EMBO Rep. 2016. PMID: 26931568 Free PMC article.

8

ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration.

Jaiswal H, Benada J, Müllers E, Akopyan K, Burdova K, Koolmeister T, Helleday T, Medema RH, Macurek L, Lindqvist A. Jaiswal H, et al. Among authors: medema rh. EMBO J. 2017 Jul 14;36(14):2161-2176. doi: 10.15252/embj.201696082. Epub 2017 Jun 12. EMBO J. 2017. PMID: 28607002 Free PMC article.

9

Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD.

Baas AF, Boudeau J, Sapkota GP, Smit L, Medema R, Morrice NA, Alessi DR, Clevers HC. Baas AF, et al. EMBO J. 2003 Jun 16;22(12):3062-72. doi: 10.1093/emboj/cdg292. EMBO J. 2003. PMID: 12805220 Free PMC article.

10

Ablation of the spindle assembly checkpoint by a compound targeting Mps1.

Schmidt M, Budirahardja Y, Klompmaker R, Medema RH. Schmidt M, et al. Among authors: medema rh. EMBO Rep. 2005 Sep;6(9):866-72. doi: 10.1038/sj.embor.7400483. EMBO Rep. 2005. PMID: 16113653 Free PMC article.

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