Eccles SA - Search Results

1

CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs.

Walton MI, Eve PD, Hayes A, Valenti MR, De Haven Brandon AK, Box G, Hallsworth A, Smith EL, Boxall KJ, Lainchbury M, Matthews TP, Jamin Y, Robinson SP, Aherne GW, Reader JC, Chesler L, Raynaud FI, Eccles SA, Collins I, Garrett MD. Walton MI, et al. Among authors: eccles sa. Clin Cancer Res. 2012 Oct 15;18(20):5650-61. doi: 10.1158/1078-0432.CCR-12-1322. Epub 2012 Aug 28. Clin Cancer Res. 2012. PMID: 22929806 Free PMC article.

2

Immunotherapy of human tumour xenografts overexpressing the EGF receptor with rat antibodies that block growth factor-receptor interaction.

Modjtahedi H, Eccles S, Box G, Styles J, Dean C. Modjtahedi H, et al. Br J Cancer. 1993 Feb;67(2):254-61. doi: 10.1038/bjc.1993.49. Br J Cancer. 1993. PMID: 7679281 Free PMC article.

3

Differentiation or immune destruction: two pathways for therapy of squamous cell carcinomas with antibodies to the epidermal growth factor receptor.

Modjtahedi H, Eccles S, Sandle J, Box G, Titley J, Dean C. Modjtahedi H, et al. Cancer Res. 1994 Apr 1;54(7):1695-701. Cancer Res. 1994. PMID: 8137284

4

Immunotherapy with antibodies to the EGF receptor.

Dean C, Modjtahedi H, Eccles S, Box G, Styles J. Dean C, et al. Int J Cancer Suppl. 1994;8:103-7. doi: 10.1002/ijc.2910570722. Int J Cancer Suppl. 1994. PMID: 8194887

5

Phosphocholine and choline content of rat sarcoma cells grown in the presence and absence of serum.

Smith TA, Eccles S, Box G, Titley JC, Leach MO, McCready VR. Smith TA, et al. Anticancer Res. 1996 May-Jun;16(3B):1389-92. Anticancer Res. 1996. PMID: 8694506

6

In vivo efficacy of XR9051, a potent modulator of P-glycoprotein mediated multidrug resistance.

Mistry P, Plumb J, Eccles S, Watson S, Dale I, Ryder H, Box G, Charlton P, Templeton D, Bevan PB. Mistry P, et al. Br J Cancer. 1999 Apr;79(11-12):1672-8. doi: 10.1038/sj.bjc.6690267. Br J Cancer. 1999. PMID: 10206276 Free PMC article.

7

Overexpression of epidermal growth factor receptor in human head and neck squamous carcinoma cell lines correlates with matrix metalloproteinase-9 expression and in vitro invasion.

O-Charoenrat P, Rhys-Evans P, Modjtahedi H, Court W, Box G, Eccles S. O-Charoenrat P, et al. Int J Cancer. 2000 May 1;86(3):307-17. doi: 10.1002/(sici)1097-0215(20000501)86:3<307::aid-ijc2>3.0.co;2-i. Int J Cancer. 2000. PMID: 10760816

8

Hyaluronidase gene profiling and role of hyal-1 overexpression in an orthotopic model of prostate cancer.

Patel S, Turner PR, Stubberfield C, Barry E, Rohlff CR, Stamps A, McKenzie E, Young K, Tyson K, Terrett J, Box G, Eccles S, Page MJ. Patel S, et al. Int J Cancer. 2002 Feb 1;97(4):416-24. doi: 10.1002/ijc.1638. Int J Cancer. 2002. PMID: 11802201

9

Targeting of cells expressing wild-type EGFR and type-III mutant EGFR (EGFRvIII) by anti-EGFR MAb ICR62: a two-pronged attack for tumour therapy.

Modjtahedi H, Moscatello DK, Box G, Green M, Shotton C, Lamb DJ, Reynolds LJ, Wong AJ, Dean C, Thomas H, Eccles S. Modjtahedi H, et al. Int J Cancer. 2003 Jun 10;105(2):273-80. doi: 10.1002/ijc.11055. Int J Cancer. 2003. PMID: 12673691

10

Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo.

Spruce BA, Campbell LA, McTavish N, Cooper MA, Appleyard MV, O'Neill M, Howie J, Samson J, Watt S, Murray K, McLean D, Leslie NR, Safrany ST, Ferguson MJ, Peters JA, Prescott AR, Box G, Hayes A, Nutley B, Raynaud F, Downes CP, Lambert JJ, Thompson AM, Eccles S. Spruce BA, et al. Cancer Res. 2004 Jul 15;64(14):4875-86. doi: 10.1158/0008-5472.CAN-03-3180. Cancer Res. 2004. PMID: 15256458

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