Adkins KK - Search Results

1

Reproductive performance and early postnatal development in interleukin (IL)-13-deficient mice.

Wright DJ, Adkins KK, Minck DR, Bailey S, Warner G, Leach MW. Wright DJ, et al. Among authors: adkins kk. Birth Defects Res B Dev Reprod Toxicol. 2012 Oct;95(5):346-53. doi: 10.1002/bdrb.21023. Epub 2012 Aug 28. Birth Defects Res B Dev Reprod Toxicol. 2012. PMID: 22930549

2

A Synopsis of the "Influence of Epigenetics, Genetics, and Immunology" Session Part A at the 35th Annual Society of Toxicologic Pathology Symposium.

Harrill AH, Moggs JG, Adkins KK, Augustin HG, Johnson RC, Leach MW. Harrill AH, et al. Among authors: adkins kk. Toxicol Pathol. 2017 Jan;45(1):114-118. doi: 10.1177/0192623316670781. Epub 2016 Oct 5. Toxicol Pathol. 2017. PMID: 27708198 Review.

3

Correlation of pharmacodynamic activity, pharmacokinetics, and anti-product antibody responses to anti-IL-21R antibody therapeutics following IV administration to cynomolgus monkeys.

Vugmeyster Y, Allen S, Szklut P, Bree A, Ryan M, Ma M, Spaulding V, Young D, Guay H, Bloom L, Leach MW, O'Toole M, Adkins K. Vugmeyster Y, et al. J Transl Med. 2010 Apr 26;8:41. doi: 10.1186/1479-5876-8-41. J Transl Med. 2010. PMID: 20420683 Free PMC article.

4

Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.

Martone RL, Zhou H, Atchison K, Comery T, Xu JZ, Huang X, Gong X, Jin M, Kreft A, Harrison B, Mayer SC, Aschmies S, Gonzales C, Zaleska MM, Riddell DR, Wagner E, Lu P, Sun SC, Sonnenberg-Reines J, Oganesian A, Adkins K, Leach MW, Clarke DW, Huryn D, Abou-Gharbia M, Magolda R, Bard J, Frick G, Raje S, Forlow SB, Balliet C, Burczynski ME, Reinhart PH, Wan HI, Pangalos MN, Jacobsen JS. Martone RL, et al. J Pharmacol Exp Ther. 2009 Nov;331(2):598-608. doi: 10.1124/jpet.109.152975. Epub 2009 Aug 11. J Pharmacol Exp Ther. 2009. PMID: 19671883

5

Dysregulation of protein degradation pathways may mediate the liver injury and phospholipidosis associated with a cationic amphiphilic antibiotic drug.

Mosedale M, Wu H, Kurtz CL, Schmidt SP, Adkins K, Harrill AH. Mosedale M, et al. Toxicol Appl Pharmacol. 2014 Oct 1;280(1):21-9. doi: 10.1016/j.taap.2014.06.013. Epub 2014 Jun 23. Toxicol Appl Pharmacol. 2014. PMID: 24967691

6

A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.

Church RJ, Wu H, Mosedale M, Sumner SJ, Pathmasiri W, Kurtz CL, Pletcher MT, Eaddy JS, Pandher K, Singer M, Batheja A, Watkins PB, Adkins K, Harrill AH. Church RJ, et al. Toxicol Sci. 2014 Aug 1;140(2):481-92. doi: 10.1093/toxsci/kfu094. Epub 2014 May 20. Toxicol Sci. 2014. PMID: 24848797 Free PMC article.

7

Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood.

Arai M, Jain S, Weaver AA, Hill AA, Guo Y, Bree AG, Smith MF Jr, Allen SW, LaVallie ER, Young D, Bloom L, Adkins K, O'Toole M. Arai M, et al. J Transl Med. 2010 May 28;8:51. doi: 10.1186/1479-5876-8-51. J Transl Med. 2010. PMID: 20509950 Free PMC article.

8

Scientific and Regulatory Policy Committee Points to Consider*: Approaches to the Conduct and Interpretation of Vaccine Safety Studies for Clinical and Anatomic Pathologists.

Sellers RS, Nelson K, Bennet B, Wolf J, Tripathi N, Chamanza R, Perron Lepage MF, Adkins K, Laurent S, Troth SP. Sellers RS, et al. Toxicol Pathol. 2020 Feb;48(2):257-276. doi: 10.1177/0192623319875085. Epub 2019 Oct 8. Toxicol Pathol. 2020. PMID: 31594486

9

Identification of polymorphisms in genes of the immune system in cynomolgus macaques.

Wu H, Adkins K. Wu H, et al. Mamm Genome. 2012 Aug;23(7-8):467-77. doi: 10.1007/s00335-012-9399-x. Epub 2012 Apr 22. Mamm Genome. 2012. PMID: 22527486

10

Principles of precision medicine and its application in toxicology.

Cook JC, Wu H, Aleo MD, Adkins K. Cook JC, et al. J Toxicol Sci. 2018;43(10):565-577. doi: 10.2131/jts.43.565. J Toxicol Sci. 2018. PMID: 30298845 Free article. Review.

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