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Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules.
Hedvat M, Emdad L, Das SK, Kim K, Dasgupta S, Thomas S, Hu B, Zhu S, Dash R, Quinn BA, Oyesanya RA, Kegelman TP, Sokhi UK, Sarkar S, Erdogan E, Menezes ME, Bhoopathi P, Wang XY, Pomper MG, Wei J, Wu B, Stebbins JL, Diaz PW, Reed JC, Pellecchia M, Sarkar D, Fisher PB. Hedvat M, et al. Among authors: das sk. Anticancer Agents Med Chem. 2012 Nov;12(9):1143-55. doi: 10.2174/187152012803529709. Anticancer Agents Med Chem. 2012. PMID: 22931411 Free PMC article. Review.
mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.
Dash R, Bhutia SK, Azab B, Su ZZ, Quinn BA, Kegelmen TP, Das SK, Kim K, Lee SG, Park MA, Yacoub A, Rahmani M, Emdad L, Dmitriev IP, Wang XY, Sarkar D, Grant S, Dent P, Curiel DT, Fisher PB. Dash R, et al. Among authors: das sk. Cytokine Growth Factor Rev. 2010 Oct;21(5):381-91. doi: 10.1016/j.cytogfr.2010.08.004. Cytokine Growth Factor Rev. 2010. PMID: 20926331 Free PMC article. Review.
Astrocyte elevated gene-1 induces protective autophagy.
Bhutia SK, Kegelman TP, Das SK, Azab B, Su ZZ, Lee SG, Sarkar D, Fisher PB. Bhutia SK, et al. Among authors: das sk. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22243-8. doi: 10.1073/pnas.1009479107. Epub 2010 Dec 2. Proc Natl Acad Sci U S A. 2010. PMID: 21127263 Free PMC article.
Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity.
Dash R, Azab B, Quinn BA, Shen X, Wang XY, Das SK, Rahmani M, Wei J, Hedvat M, Dent P, Dmitriev IP, Curiel DT, Grant S, Wu B, Stebbins JL, Pellecchia M, Reed JC, Sarkar D, Fisher PB. Dash R, et al. Among authors: das sk. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8785-90. doi: 10.1073/pnas.1100769108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555592 Free PMC article.
2,555 results