Diaz PW - Search Results

1

Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules.

Hedvat M, Emdad L, Das SK, Kim K, Dasgupta S, Thomas S, Hu B, Zhu S, Dash R, Quinn BA, Oyesanya RA, Kegelman TP, Sokhi UK, Sarkar S, Erdogan E, Menezes ME, Bhoopathi P, Wang XY, Pomper MG, Wei J, Wu B, Stebbins JL, Diaz PW, Reed JC, Pellecchia M, Sarkar D, Fisher PB. Hedvat M, et al. Among authors: diaz pw. Anticancer Agents Med Chem. 2012 Nov;12(9):1143-55. doi: 10.2174/187152012803529709. Anticancer Agents Med Chem. 2012. PMID: 22931411 Free PMC article. Review.

2

Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors.

Correa RG, Khan PM, Askari N, Zhai D, Gerlic M, Brown B, Magnuson G, Spreafico R, Albani S, Sergienko E, Diaz PW, Roth GP, Reed JC. Correa RG, et al. Among authors: diaz pw. Chem Biol. 2011 Jul 29;18(7):825-32. doi: 10.1016/j.chembiol.2011.06.009. Chem Biol. 2011. PMID: 21802003 Free PMC article.

3

Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins.

Hassig CA, Zeng FY, Kung P, Kiankarimi M, Kim S, Diaz PW, Zhai D, Welsh K, Morshedian S, Su Y, O'Keefe B, Newman DJ, Rusman Y, Kaur H, Salomon CE, Brown SG, Baire B, Michel AR, Hoye TR, Francis S, Georg GI, Walters MA, Divlianska DB, Roth GP, Wright AE, Reed JC. Hassig CA, et al. Among authors: diaz pw. J Biomol Screen. 2014 Sep;19(8):1201-11. doi: 10.1177/1087057114536227. Epub 2014 May 27. J Biomol Screen. 2014. PMID: 24870016 Free PMC article.

4

High-throughput fluorescence polarization assay for chemical library screening against anti-apoptotic Bcl-2 family member Bfl-1.

Zhai D, Godoi P, Sergienko E, Dahl R, Chan X, Brown B, Rascon J, Hurder A, Su Y, Chung TD, Jin C, Diaz P, Reed JC. Zhai D, et al. J Biomol Screen. 2012 Mar;17(3):350-60. doi: 10.1177/1087057111429372. Epub 2011 Dec 7. J Biomol Screen. 2012. PMID: 22156224

5

High-throughput fluorescence assay for small-molecule inhibitors of autophagins/Atg4.

Shu CW, Madiraju C, Zhai D, Welsh K, Diaz P, Sergienko E, Sano R, Reed JC. Shu CW, et al. J Biomol Screen. 2011 Feb;16(2):174-82. doi: 10.1177/1087057110392996. Epub 2011 Jan 18. J Biomol Screen. 2011. PMID: 21245471

6

Endoplasmic reticulum protein BI-1 regulates Ca²⁺-mediated bioenergetics to promote autophagy.

Sano R, Hou YC, Hedvat M, Correa RG, Shu CW, Krajewska M, Diaz PW, Tamble CM, Quarato G, Gottlieb RA, Yamaguchi M, Nizet V, Dahl R, Thomas DD, Tait SW, Green DR, Fisher PB, Matsuzawa S, Reed JC. Sano R, et al. Among authors: diaz pw. Genes Dev. 2012 May 15;26(10):1041-54. doi: 10.1101/gad.184325.111. Genes Dev. 2012. PMID: 22588718 Free PMC article.

7

Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics.

Kim K, Lee SG, Kegelman TP, Su ZZ, Das SK, Dash R, Dasgupta S, Barral PM, Hedvat M, Diaz P, Reed JC, Stebbins JL, Pellecchia M, Sarkar D, Fisher PB. Kim K, et al. J Cell Physiol. 2011 Oct;226(10):2484-93. doi: 10.1002/jcp.22609. J Cell Physiol. 2011. PMID: 21792905 Free PMC article. Review.

8

Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1.

Rong J, Pass I, Diaz PW, Ngo TA, Sauer M, Magnuson G, Zeng FY, Hassig CA, Jackson MR, Cosford ND, Matsuzawa S, Reed JC. Rong J, et al. Among authors: diaz pw. J Biomol Screen. 2015 Dec;20(10):1232-45. doi: 10.1177/1087057115600414. Epub 2015 Aug 11. J Biomol Screen. 2015. PMID: 26265713

9

Versatile assays for high throughput screening for activators or inhibitors of intracellular proteases and their cellular regulators.

Hayashi H, Cuddy M, Shu VC, Yip KW, Madiraju C, Diaz P, Matsuyama T, Kaibara M, Taniyama K, Vasile S, Sergienko E, Reed JC. Hayashi H, et al. PLoS One. 2009 Oct 30;4(10):e7655. doi: 10.1371/journal.pone.0007655. PLoS One. 2009. PMID: 19876397 Free PMC article.

10

TR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors.

Madiraju C, Welsh K, Cuddy MP, Godoi PH, Pass I, Ngo T, Vasile S, Sergienko EA, Diaz P, Matsuzawa S, Reed JC. Madiraju C, et al. J Biomol Screen. 2012 Feb;17(2):163-76. doi: 10.1177/1087057111423417. Epub 2011 Oct 27. J Biomol Screen. 2012. PMID: 22034497 Free PMC article.

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