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Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules.
Hedvat M, Emdad L, Das SK, Kim K, Dasgupta S, Thomas S, Hu B, Zhu S, Dash R, Quinn BA, Oyesanya RA, Kegelman TP, Sokhi UK, Sarkar S, Erdogan E, Menezes ME, Bhoopathi P, Wang XY, Pomper MG, Wei J, Wu B, Stebbins JL, Diaz PW, Reed JC, Pellecchia M, Sarkar D, Fisher PB. Hedvat M, et al. Among authors: kegelman tp. Anticancer Agents Med Chem. 2012 Nov;12(9):1143-55. doi: 10.2174/187152012803529709. Anticancer Agents Med Chem. 2012. PMID: 22931411 Free PMC article. Review.
Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin.
Kegelman TP, Wu B, Das SK, Talukdar S, Beckta JM, Hu B, Emdad L, Valerie K, Sarkar D, Furnari FB, Cavenee WK, Wei J, Purves A, De SK, Pellecchia M, Fisher PB. Kegelman TP, et al. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):370-375. doi: 10.1073/pnas.1616100114. Epub 2016 Dec 23. Proc Natl Acad Sci U S A. 2017. PMID: 28011764 Free PMC article.
MDA-9/syntenin and IGFBP-2 promote angiogenesis in human melanoma.
Das SK, Bhutia SK, Azab B, Kegelman TP, Peachy L, Santhekadur PK, Dasgupta S, Dash R, Dent P, Grant S, Emdad L, Pellecchia M, Sarkar D, Fisher PB. Das SK, et al. Among authors: kegelman tp. Cancer Res. 2013 Jan 15;73(2):844-54. doi: 10.1158/0008-5472.CAN-12-1681. Epub 2012 Dec 10. Cancer Res. 2013. PMID: 23233738 Free PMC article.
MDA-9/syntenin is a key regulator of glioma pathogenesis.
Kegelman TP, Das SK, Hu B, Bacolod MD, Fuller CE, Menezes ME, Emdad L, Dasgupta S, Baldwin AS, Bruce JN, Dent P, Pellecchia M, Sarkar D, Fisher PB. Kegelman TP, et al. Neuro Oncol. 2014 Jan;16(1):50-61. doi: 10.1093/neuonc/not157. Epub 2013 Dec 4. Neuro Oncol. 2014. PMID: 24305713 Free PMC article.
Targeting tumor invasion: the roles of MDA-9/Syntenin.
Kegelman TP, Das SK, Emdad L, Hu B, Menezes ME, Bhoopathi P, Wang XY, Pellecchia M, Sarkar D, Fisher PB. Kegelman TP, et al. Expert Opin Ther Targets. 2015 Jan;19(1):97-112. doi: 10.1517/14728222.2014.959495. Epub 2014 Sep 15. Expert Opin Ther Targets. 2015. PMID: 25219541 Free PMC article. Review.
22 results