Rupasinghe SG - Search Results

1

A gain-of-function polymorphism controlling complex traits and fitness in nature.

Prasad KV, Song BH, Olson-Manning C, Anderson JT, Lee CR, Schranz ME, Windsor AJ, Clauss MJ, Manzaneda AJ, Naqvi I, Reichelt M, Gershenzon J, Rupasinghe SG, Schuler MA, Mitchell-Olds T. Prasad KV, et al. Among authors: rupasinghe sg. Science. 2012 Aug 31;337(6098):1081-4. doi: 10.1126/science.1221636. Science. 2012. PMID: 22936775 Free PMC article.

2

Allelic variation in the Depressaria pastinacella CYP6AB3 protein enhances metabolism of plant allelochemicals by altering a proximal surface residue and potential interactions with cytochrome P450 reductase.

Mao W, Rupasinghe SG, Zangerl AR, Berenbaum MR, Schuler MA. Mao W, et al. Among authors: rupasinghe sg. J Biol Chem. 2007 Apr 6;282(14):10544-52. doi: 10.1074/jbc.M607946200. Epub 2007 Jan 23. J Biol Chem. 2007. PMID: 17244619 Free article.

3

Comparative molecular modeling of Anopheles gambiae CYP6Z1, a mosquito P450 capable of metabolizing DDT.

Chiu TL, Wen Z, Rupasinghe SG, Schuler MA. Chiu TL, et al. Among authors: rupasinghe sg. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):8855-60. doi: 10.1073/pnas.0709249105. Epub 2008 Jun 24. Proc Natl Acad Sci U S A. 2008. PMID: 18577597 Free PMC article.

4

Common active site architecture and binding strategy of four phenylpropanoid P450s from Arabidopsis thaliana as revealed by molecular modeling.

Rupasinghe S, Baudry J, Schuler MA. Rupasinghe S, et al. Protein Eng. 2003 Oct;16(10):721-31. doi: 10.1093/protein/gzg094. Protein Eng. 2003. PMID: 14600201

5

Class-dependent sequence alignment strategy improves the structural and functional modeling of P450s.

Baudry J, Rupasinghe S, Schuler MA. Baudry J, et al. Protein Eng Des Sel. 2006 Aug;19(8):345-53. doi: 10.1093/protein/gzl012. Epub 2006 Jun 15. Protein Eng Des Sel. 2006. PMID: 16777908

6

CYP6B1 and CYP6B3 of the black swallowtail (Papilio polyxenes): adaptive evolution through subfunctionalization.

Wen Z, Rupasinghe S, Niu G, Berenbaum MR, Schuler MA. Wen Z, et al. Mol Biol Evol. 2006 Dec;23(12):2434-43. doi: 10.1093/molbev/msl118. Epub 2006 Sep 19. Mol Biol Evol. 2006. PMID: 16984951

7

Arabidopsis CYP72C1 is an atypical cytochrome P450 that inactivates brassinosteroids.

Thornton LE, Rupasinghe SG, Peng H, Schuler MA, Neff MM. Thornton LE, et al. Among authors: rupasinghe sg. Plant Mol Biol. 2010 Sep;74(1-2):167-81. doi: 10.1007/s11103-010-9663-y. Epub 2010 Jul 30. Plant Mol Biol. 2010. PMID: 20669042

8

Gravity Persistent Signal 1 (GPS1) reveals novel cytochrome P450s involved in gravitropism.

Withers JC, Shipp MJ, Rupasinghe SG, Sukumar P, Schuler MA, Muday GK, Wyatt SE. Withers JC, et al. Among authors: rupasinghe sg. Am J Bot. 2013 Jan;100(1):183-93. doi: 10.3732/ajb.1200436. Am J Bot. 2013. PMID: 23284057 Free article.

9

Helicoverpa zea CYP6B8 and CYP321A1: different molecular solutions to the problem of metabolizing plant toxins and insecticides.

Rupasinghe SG, Wen Z, Chiu TL, Schuler MA. Rupasinghe SG, et al. Protein Eng Des Sel. 2007 Dec;20(12):615-24. doi: 10.1093/protein/gzm063. Epub 2007 Dec 6. Protein Eng Des Sel. 2007. PMID: 18065401

10

High-yield expression and purification of isotopically labeled cytochrome P450 monooxygenases for solid-state NMR spectroscopy.

Rupasinghe SG, Duan H, Frericks Schmidt HL, Berthold DA, Rienstra CM, Schuler MA. Rupasinghe SG, et al. Biochim Biophys Acta. 2007 Dec;1768(12):3061-70. doi: 10.1016/j.bbamem.2007.09.009. Epub 2007 Sep 25. Biochim Biophys Acta. 2007. PMID: 18005930 Free PMC article.

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