Kehry MR - Search Results

1

EC144 is a potent inhibitor of the heat shock protein 90.

Shi J, Van de Water R, Hong K, Lamer RB, Weichert KW, Sandoval CM, Kasibhatla SR, Boehm MF, Chao J, Lundgren K, Timple N, Lough R, Ibanez G, Boykin C, Burrows FJ, Kehry MR, Yun TJ, Harning EK, Ambrose C, Thompson J, Bixler SA, Dunah A, Snodgrass-Belt P, Arndt J, Enyedy IJ, Li P, Hong VS, McKenzie A, Biamonte MA. Shi J, et al. Among authors: kehry mr. J Med Chem. 2012 Sep 13;55(17):7786-95. doi: 10.1021/jm300810x. Epub 2012 Aug 31. J Med Chem. 2012. PMID: 22938030

2

EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity.

Yun TJ, Harning EK, Giza K, Rabah D, Li P, Arndt JW, Luchetti D, Biamonte MA, Shi J, Lundgren K, Manning A, Kehry MR. Yun TJ, et al. Among authors: kehry mr. J Immunol. 2011 Jan 1;186(1):563-75. doi: 10.4049/jimmunol.1000222. Epub 2010 Dec 3. J Immunol. 2011. PMID: 21131419

3

An intermediate pH unfolding transition abrogates the ability of IgE to interact with its high affinity receptor FcepsilonRIalpha.

Demarest SJ, Hopp J, Chung J, Hathaway K, Mertsching E, Cao X, George J, Miatkowski K, LaBarre MJ, Shields M, Kehry MR. Demarest SJ, et al. Among authors: kehry mr. J Biol Chem. 2006 Oct 13;281(41):30755-67. doi: 10.1074/jbc.M605190200. Epub 2006 Aug 11. J Biol Chem. 2006. PMID: 16905745 Free article.

4

A mouse Fcgamma-Fcepsilon protein that inhibits mast cells through activation of FcgammaRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases.

Mertsching E, Bafetti L, Hess H, Perper S, Giza K, Allen LC, Negrou E, Hathaway K, Hopp J, Chung J, Perret D, Shields M, Saxon A, Kehry MR. Mertsching E, et al. Among authors: kehry mr. J Allergy Clin Immunol. 2008 Feb;121(2):441-447.e5. doi: 10.1016/j.jaci.2007.08.051. Epub 2007 Oct 18. J Allergy Clin Immunol. 2008. PMID: 17949802

5

B-cell depletion with anti-CD20 ameliorates autoimmune cholangitis but exacerbates colitis in transforming growth factor-beta receptor II dominant negative mice.

Moritoki Y, Lian ZX, Lindor K, Tuscano J, Tsuneyama K, Zhang W, Ueno Y, Dunn R, Kehry M, Coppel RL, Mackay IR, Gershwin ME. Moritoki Y, et al. Hepatology. 2009 Dec;50(6):1893-903. doi: 10.1002/hep.23238. Hepatology. 2009. PMID: 19877182 Free PMC article.

6

B cell depletion enhances T regulatory cell activity essential in the suppression of arthritis.

Hamel KM, Cao Y, Ashaye S, Wang Y, Dunn R, Kehry MR, Glant TT, Finnegan A. Hamel KM, et al. Among authors: kehry mr. J Immunol. 2011 Nov 1;187(9):4900-6. doi: 10.4049/jimmunol.1101844. Epub 2011 Sep 23. J Immunol. 2011. PMID: 21948985 Free PMC article.

7

Depletion of B cells in murine lupus: efficacy and resistance.

Ahuja A, Shupe J, Dunn R, Kashgarian M, Kehry MR, Shlomchik MJ. Ahuja A, et al. Among authors: kehry mr. J Immunol. 2007 Sep 1;179(5):3351-61. doi: 10.4049/jimmunol.179.5.3351. J Immunol. 2007. PMID: 17709552

8

Ligation of CD28 in vivo induces CD40 ligand expression and promotes B cell survival.

Yin D, Zhang L, Wang R, Radvanyi L, Haudenschild C, Fang Q, Kehry MR, Shi Y. Yin D, et al. Among authors: kehry mr. J Immunol. 1999 Oct 15;163(8):4328-34. J Immunol. 1999. PMID: 10510372

9

An acquired defect in IgG-dependent phagocytosis explains the impairment in antibody-mediated cellular depletion in Lupus.

Ahuja A, Teichmann LL, Wang H, Dunn R, Kehry MR, Shlomchik MJ. Ahuja A, et al. Among authors: kehry mr. J Immunol. 2011 Oct 1;187(7):3888-94. doi: 10.4049/jimmunol.1101629. Epub 2011 Aug 26. J Immunol. 2011. PMID: 21873531 Free PMC article.

10

B cell depletion inhibits spontaneous autoimmune thyroiditis in NOD.H-2h4 mice.

Yu S, Dunn R, Kehry MR, Braley-Mullen H. Yu S, et al. Among authors: kehry mr. J Immunol. 2008 Jun 1;180(11):7706-13. doi: 10.4049/jimmunol.180.11.7706. J Immunol. 2008. PMID: 18490774

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