Certo MT - Search Results

1

Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.

Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, Scharenberg AM. Certo MT, et al. Nat Methods. 2012 Oct;9(10):973-5. doi: 10.1038/nmeth.2177. Epub 2012 Sep 2. Nat Methods. 2012. PMID: 22941364 Free PMC article.

2

Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation.

Takeuchi R, Certo M, Caprara MG, Scharenberg AM, Stoddard BL. Takeuchi R, et al. Nucleic Acids Res. 2009 Feb;37(3):877-90. doi: 10.1093/nar/gkn1007. Epub 2008 Dec 22. Nucleic Acids Res. 2009. PMID: 19103658 Free PMC article.

3

High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.

Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM. Jarjour J, et al. Among authors: certo mt. Nucleic Acids Res. 2009 Nov;37(20):6871-80. doi: 10.1093/nar/gkp726. Epub 2009 Sep 8. Nucleic Acids Res. 2009. PMID: 19740766 Free PMC article.

4

Tracking genome engineering outcome at individual DNA breakpoints.

Certo MT, Ryu BY, Annis JE, Garibov M, Jarjour J, Rawlings DJ, Scharenberg AM. Certo MT, et al. Nat Methods. 2011 Jul 10;8(8):671-6. doi: 10.1038/nmeth.1648. Nat Methods. 2011. PMID: 21743461 Free PMC article.

5

Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space.

Jacoby K, Metzger M, Shen BW, Certo MT, Jarjour J, Stoddard BL, Scharenberg AM. Jacoby K, et al. Among authors: certo mt. Nucleic Acids Res. 2012 Jun;40(11):4954-64. doi: 10.1093/nar/gkr1303. Epub 2012 Feb 14. Nucleic Acids Res. 2012. PMID: 22334611 Free PMC article.

6

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.

Ramirez CL, Certo MT, Mussolino C, Goodwin MJ, Cradick TJ, McCaffrey AP, Cathomen T, Scharenberg AM, Joung JK. Ramirez CL, et al. Among authors: certo mt. Nucleic Acids Res. 2012 Jul;40(12):5560-8. doi: 10.1093/nar/gks179. Epub 2012 Feb 28. Nucleic Acids Res. 2012. PMID: 22373919 Free PMC article.

7

Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks.

Kuhar R, Gwiazda KS, Humbert O, Mandt T, Pangallo J, Brault M, Khan I, Maizels N, Rawlings DJ, Scharenberg AM, Certo MT. Kuhar R, et al. Among authors: certo mt. Nucleic Acids Res. 2014 Jan;42(1):e4. doi: 10.1093/nar/gkt872. Epub 2013 Oct 10. Nucleic Acids Res. 2014. PMID: 24121685 Free PMC article.

8

megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.

Boissel S, Jarjour J, Astrakhan A, Adey A, Gouble A, Duchateau P, Shendure J, Stoddard BL, Certo MT, Baker D, Scharenberg AM. Boissel S, et al. Among authors: certo mt. Nucleic Acids Res. 2014 Feb;42(4):2591-601. doi: 10.1093/nar/gkt1224. Epub 2013 Nov 26. Nucleic Acids Res. 2014. PMID: 24285304 Free PMC article.

9

Design and analysis of site-specific single-strand nicking endonucleases for gene correction.

Metzger MJ, Certo MT. Metzger MJ, et al. Among authors: certo mt. Methods Mol Biol. 2014;1114:237-44. doi: 10.1007/978-1-62703-761-7_15. Methods Mol Biol. 2014. PMID: 24557907

10

Optimizing 5'UTRs for mRNA-delivered gene editing using deep learning.

Castillo-Hair S, Fedak S, Wang B, Linder J, Havens K, Certo M, Seelig G. Castillo-Hair S, et al. Nat Commun. 2024 Jun 20;15(1):5284. doi: 10.1038/s41467-024-49508-2. Nat Commun. 2024. PMID: 38902240 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

14 results

Search Page

Filters