Kirik D - Search Results

1

Transduced wild-type but not P301S mutated human tau shows hyperphosphorylation in transgenic mice overexpressing A30P mutated human alpha-synuclein.

Oksman M, Wisman LA, Jiang H, Miettinen P, Kirik D, Tanila H. Oksman M, et al. Among authors: kirik d. Neurodegener Dis. 2013;12(2):91-102. doi: 10.1159/000341596. Epub 2012 Aug 30. Neurodegener Dis. 2013. PMID: 22948283

2

Functional convergence of dopaminergic and cholinergic input is critical for hippocampus-dependent working memory.

Wisman LA, Sahin G, Maingay M, Leanza G, Kirik D. Wisman LA, et al. Among authors: kirik d. J Neurosci. 2008 Jul 30;28(31):7797-807. doi: 10.1523/JNEUROSCI.1885-08.2008. J Neurosci. 2008. PMID: 18667612 Free PMC article.

3

Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain.

Kornum BR, Stott SR, Mattsson B, Wisman L, Ettrup A, Hermening S, Knudsen GM, Kirik D. Kornum BR, et al. Among authors: kirik d. Exp Neurol. 2010 Mar;222(1):70-85. doi: 10.1016/j.expneurol.2009.12.009. Epub 2009 Dec 16. Exp Neurol. 2010. PMID: 20025873

4

Characterization of cognitive deficits in rats overexpressing human alpha-synuclein in the ventral tegmental area and medial septum using recombinant adeno-associated viral vectors.

Hall H, Jewett M, Landeck N, Nilsson N, Schagerlöf U, Leanza G, Kirik D. Hall H, et al. Among authors: kirik d. PLoS One. 2013 May 21;8(5):e64844. doi: 10.1371/journal.pone.0064844. Print 2013. PLoS One. 2013. PMID: 23705016 Free PMC article.

5

Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain.

Eslamboli A, Romero-Ramos M, Burger C, Bjorklund T, Muzyczka N, Mandel RJ, Baker H, Ridley RM, Kirik D. Eslamboli A, et al. Among authors: kirik d. Brain. 2007 Mar;130(Pt 3):799-815. doi: 10.1093/brain/awl382. Epub 2007 Feb 15. Brain. 2007. PMID: 17303591

6

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

Kirik D, Rosenblad C, Burger C, Lundberg C, Johansen TE, Muzyczka N, Mandel RJ, Björklund A. Kirik D, et al. J Neurosci. 2002 Apr 1;22(7):2780-91. doi: 10.1523/JNEUROSCI.22-07-02780.2002. J Neurosci. 2002. PMID: 11923443 Free PMC article.

7

In vivo quantification of glial activation in minipigs overexpressing human α-synuclein.

Lillethorup TP, Glud AN, Landeck N, Alstrup AKO, Jakobsen S, Vang K, Doudet DJ, Brooks DJ, Kirik D, Hinz R, Sørensen JC, Landau AM. Lillethorup TP, et al. Among authors: kirik d. Synapse. 2018 Dec;72(12):e22060. doi: 10.1002/syn.22060. Epub 2018 Aug 12. Synapse. 2018. PMID: 30009467

8

Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates.

Elfarrash S, Jensen NM, Ferreira N, Betzer C, Thevathasan JV, Diekmann R, Adel M, Omar NM, Boraie MZ, Gad S, Ries J, Kirik D, Nabavi S, Jensen PH. Elfarrash S, et al. Among authors: kirik d. Acta Neuropathol Commun. 2019 Dec 19;7(1):213. doi: 10.1186/s40478-019-0865-5. Acta Neuropathol Commun. 2019. PMID: 31856920 Free PMC article.

9

Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease.

Kirik D, Annett LE, Burger C, Muzyczka N, Mandel RJ, Björklund A. Kirik D, et al. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2884-9. doi: 10.1073/pnas.0536383100. Epub 2003 Feb 24. Proc Natl Acad Sci U S A. 2003. PMID: 12601150 Free PMC article.

10

Ventral tegmental area dopamine neurons are resistant to human mutant alpha-synuclein overexpression.

Maingay M, Romero-Ramos M, Carta M, Kirik D. Maingay M, et al. Among authors: kirik d. Neurobiol Dis. 2006 Sep;23(3):522-32. doi: 10.1016/j.nbd.2006.04.007. Epub 2006 Jun 30. Neurobiol Dis. 2006. PMID: 16806952

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