Kervinen J - Search Results

1

Extended cleavage specificity of the mast cell chymase from the crab-eating macaque (Macaca fascicularis): an interesting animal model for the analysis of the function of the human mast cell chymase.

Thorpe M, Yu J, Boinapally V, Ahooghalandari P, Kervinen J, Garavilla Ld, Hellman L. Thorpe M, et al. Among authors: kervinen j. Int Immunol. 2012 Dec;24(12):771-82. doi: 10.1093/intimm/dxs081. Epub 2012 Sep 4. Int Immunol. 2012. PMID: 22949566

2

Highly Selective Cleavage of Cytokines and Chemokines by the Human Mast Cell Chymase and Neutrophil Cathepsin G.

Fu Z, Thorpe M, Alemayehu R, Roy A, Kervinen J, de Garavilla L, Åbrink M, Hellman L. Fu Z, et al. Among authors: kervinen j. J Immunol. 2017 Feb 15;198(4):1474-1483. doi: 10.4049/jimmunol.1601223. Epub 2017 Jan 4. J Immunol. 2017. PMID: 28053237

3

Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities.

Thorpe M, Fu Z, Chahal G, Akula S, Kervinen J, de Garavilla L, Hellman L. Thorpe M, et al. Among authors: kervinen j. PLoS One. 2018 Apr 13;13(4):e0195077. doi: 10.1371/journal.pone.0195077. eCollection 2018. PLoS One. 2018. PMID: 29652924 Free PMC article.

4

Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues.

Fu Z, Akula S, Thorpe M, Chahal G, de Garavilla L, Kervinen J, Hellman L. Fu Z, et al. Among authors: kervinen j. Dev Comp Immunol. 2019 Mar;92:160-169. doi: 10.1016/j.dci.2018.11.019. Epub 2018 Nov 24. Dev Comp Immunol. 2019. PMID: 30481523

5

Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5.

Thorpe M, Fu Z, Albat E, Akula S, de Garavilla L, Kervinen J, Hellman L. Thorpe M, et al. Among authors: kervinen j. PLoS One. 2018 Dec 6;13(12):e0207826. doi: 10.1371/journal.pone.0207826. eCollection 2018. PLoS One. 2018. PMID: 30521603 Free PMC article.

6

Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases: Two Highly Specific Leu-Ases.

Zhongwei Y, Akula S, Fu Z, de Garavilla L, Kervinen J, Thorpe M, Hellman L. Zhongwei Y, et al. Among authors: kervinen j. Int J Mol Sci. 2019 Dec 16;20(24):6340. doi: 10.3390/ijms20246340. Int J Mol Sci. 2019. PMID: 31888202 Free PMC article.

7

Duodenases are a small subfamily of ruminant intestinal serine proteases that have undergone a remarkable diversification in cleavage specificity.

Fu Z, Akula S, Qiao C, Ryu J, Chahal G, de Garavilla L, Kervinen J, Thorpe M, Hellman L. Fu Z, et al. Among authors: kervinen j. PLoS One. 2021 May 28;16(5):e0252624. doi: 10.1371/journal.pone.0252624. eCollection 2021. PLoS One. 2021. PMID: 34048501 Free PMC article.

8

Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases.

Fu Z, Akula S, Olsson AK, Kervinen J, Hellman L. Fu Z, et al. Among authors: kervinen j. Int J Mol Sci. 2021 Nov 23;22(23):12627. doi: 10.3390/ijms222312627. Int J Mol Sci. 2021. PMID: 34884431 Free PMC article.

9

Potency variation of small-molecule chymase inhibitors across species.

Kervinen J, Crysler C, Bayoumy S, Abad MC, Spurlino J, Deckman I, Greco MN, Maryanoff BE, de Garavilla L. Kervinen J, et al. Biochem Pharmacol. 2010 Oct 1;80(7):1033-41. doi: 10.1016/j.bcp.2010.06.014. Epub 2010 Jun 23. Biochem Pharmacol. 2010. PMID: 20599788

10

Cleaved SLPI, a novel biomarker of chymase activity.

Belkowski SM, Masucci J, Mahan A, Kervinen J, Olson M, de Garavilla L, D'Andrea MR. Belkowski SM, et al. Among authors: kervinen j. Biol Chem. 2008 Sep;389(9):1219-24. doi: 10.1515/BC.2008.138. Biol Chem. 2008. PMID: 18713008

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