Carlson CB - Search Results

1

Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.

Hermanson SB, Carlson CB, Riddle SM, Zhao J, Vogel KW, Nichols RJ, Bi K. Hermanson SB, et al. Among authors: carlson cb. PLoS One. 2012;7(8):e43580. doi: 10.1371/journal.pone.0043580. Epub 2012 Aug 28. PLoS One. 2012. PMID: 22952710 Free PMC article.

2

A toolbox approach to high-throughput TR-FRET-based SUMOylation and DeSUMOylation assays.

Carlson CB, Horton RA, Vogel KW. Carlson CB, et al. Assay Drug Dev Technol. 2009 Aug;7(4):348-55. doi: 10.1089/adt.2008.0188. Assay Drug Dev Technol. 2009. PMID: 19656081

3

Cellular LanthaScreen and beta-lactamase reporter assays for high-throughput screening of JAK2 inhibitors.

Robers MB, Machleidt T, Carlson CB, Bi K. Robers MB, et al. Among authors: carlson cb. Assay Drug Dev Technol. 2008 Aug;6(4):519-29. doi: 10.1089/adt.2008.144. Assay Drug Dev Technol. 2008. PMID: 18694336

4

Development of LanthaScreen cellular assays for key components within the PI3K/AKT/mTOR pathway.

Carlson CB, Robers MB, Vogel KW, Machleidt T. Carlson CB, et al. J Biomol Screen. 2009 Feb;14(2):121-32. doi: 10.1177/1087057108328132. Epub 2009 Feb 4. J Biomol Screen. 2009. PMID: 19196698

5

BacMam-enabled LanthaScreen cellular assays for PI3K/Akt pathway compound profiling in disease-relevant cell backgrounds.

Carlson CB, Mashock MJ, Bi K. Carlson CB, et al. J Biomol Screen. 2010 Mar;15(3):327-34. doi: 10.1177/1087057109357788. Epub 2010 Feb 9. J Biomol Screen. 2010. PMID: 20145103

6

Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology.

Robers MB, Loh C, Carlson CB, Yang H, Frey EA, Hermanson SB, Bi K. Robers MB, et al. Among authors: carlson cb. Mol Biosyst. 2011 Jan;7(1):59-66. doi: 10.1039/c0mb00026d. Epub 2010 Oct 8. Mol Biosyst. 2011. PMID: 20931131

7

Pharmacological inhibition of LRRK2 cellular phosphorylation sites provides insight into LRRK2 biology.

Zhao J, Hermanson SB, Carlson CB, Riddle SM, Vogel KW, Bi K, Nichols RJ. Zhao J, et al. Among authors: carlson cb. Biochem Soc Trans. 2012 Oct;40(5):1158-62. doi: 10.1042/BST20120137. Biochem Soc Trans. 2012. PMID: 22988882 Review.

8

Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent.

Ni J, Liu Q, Xie S, Carlson C, Von T, Vogel K, Riddle S, Benes C, Eck M, Roberts T, Gray N, Zhao J. Ni J, et al. Cancer Discov. 2012 May;2(5):425-33. doi: 10.1158/2159-8290.CD-12-0003. Epub 2012 Apr 12. Cancer Discov. 2012. PMID: 22588880 Free PMC article.

9

Design, synthesis, and structure-activity relationships of 3-ethynyl-1H-indazoles as inhibitors of the phosphatidylinositol 3-kinase signaling pathway.

Barile E, De SK, Carlson CB, Chen V, Knutzen C, Riel-Mehan M, Yang L, Dahl R, Chiang G, Pellecchia M. Barile E, et al. Among authors: carlson cb. J Med Chem. 2010 Dec 9;53(23):8368-75. doi: 10.1021/jm100825h. Epub 2010 Nov 9. J Med Chem. 2010. PMID: 21062009 Free PMC article.

10

Design, synthesis, and structure-activity relationship studies of thiophene-3-carboxamide derivatives as dual inhibitors of the c-Jun N-terminal kinase.

De SK, Barile E, Chen V, Stebbins JL, Cellitti JF, Machleidt T, Carlson CB, Yang L, Dahl R, Pellecchia M. De SK, et al. Among authors: carlson cb. Bioorg Med Chem. 2011 Apr 15;19(8):2582-8. doi: 10.1016/j.bmc.2011.03.017. Epub 2011 Mar 12. Bioorg Med Chem. 2011. PMID: 21458276 Free PMC article.

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