Niedernhofer LJ - Search Results

1

Broad segmental progeroid changes in short-lived Ercc1(-/Δ7) mice.

Dollé ME, Kuiper RV, Roodbergen M, Robinson J, de Vlugt S, Wijnhoven SW, Beems RB, de la Fonteyne L, de With P, van der Pluijm I, Niedernhofer LJ, Hasty P, Vijg J, Hoeijmakers JH, van Steeg H. Dollé ME, et al. Among authors: niedernhofer lj. Pathobiol Aging Age Relat Dis. 2011;1. doi: 10.3402/pba.v1i0.7219. Epub 2011 Jun 1. Pathobiol Aging Age Relat Dis. 2011. PMID: 22953029 Free PMC article.

2

The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells.

Niedernhofer LJ, Essers J, Weeda G, Beverloo B, de Wit J, Muijtjens M, Odijk H, Hoeijmakers JH, Kanaar R. Niedernhofer LJ, et al. EMBO J. 2001 Nov 15;20(22):6540-9. doi: 10.1093/emboj/20.22.6540. EMBO J. 2001. PMID: 11707424 Free PMC article.

3

Divide and conquer: nucleotide excision repair battles cancer and ageing.

Mitchell JR, Hoeijmakers JH, Niedernhofer LJ. Mitchell JR, et al. Among authors: niedernhofer lj. Curr Opin Cell Biol. 2003 Apr;15(2):232-40. doi: 10.1016/s0955-0674(03)00018-8. Curr Opin Cell Biol. 2003. PMID: 12648680 Review.

4

ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes.

Zhu XD, Niedernhofer L, Kuster B, Mann M, Hoeijmakers JH, de Lange T. Zhu XD, et al. Mol Cell. 2003 Dec;12(6):1489-98. doi: 10.1016/s1097-2765(03)00478-7. Mol Cell. 2003. PMID: 14690602 Free article.

5

The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks.

Niedernhofer LJ, Odijk H, Budzowska M, van Drunen E, Maas A, Theil AF, de Wit J, Jaspers NG, Beverloo HB, Hoeijmakers JH, Kanaar R. Niedernhofer LJ, et al. Mol Cell Biol. 2004 Jul;24(13):5776-87. doi: 10.1128/MCB.24.13.5776-5787.2004. Mol Cell Biol. 2004. PMID: 15199134 Free PMC article.

6

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions.

Schrader CE, Vardo J, Linehan E, Twarog MZ, Niedernhofer LJ, Hoeijmakers JH, Stavnezer J. Schrader CE, et al. Among authors: niedernhofer lj. J Exp Med. 2004 Aug 2;200(3):321-30. doi: 10.1084/jem.20040052. Epub 2004 Jul 26. J Exp Med. 2004. PMID: 15280420 Free PMC article.

7

Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice.

Prasher JM, Lalai AS, Heijmans-Antonissen C, Ploemacher RE, Hoeijmakers JH, Touw IP, Niedernhofer LJ. Prasher JM, et al. Among authors: niedernhofer lj. EMBO J. 2005 Feb 23;24(4):861-71. doi: 10.1038/sj.emboj.7600542. Epub 2005 Feb 3. EMBO J. 2005. PMID: 15692571 Free PMC article.

8

Fanconi anemia (cross)linked to DNA repair.

Niedernhofer LJ, Lalai AS, Hoeijmakers JH. Niedernhofer LJ, et al. Cell. 2005 Dec 29;123(7):1191-8. doi: 10.1016/j.cell.2005.12.009. Cell. 2005. PMID: 16377561 Free article. Review.

9

Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice.

Dollé ME, Busuttil RA, Garcia AM, Wijnhoven S, van Drunen E, Niedernhofer LJ, van der Horst G, Hoeijmakers JH, van Steeg H, Vijg J. Dollé ME, et al. Among authors: niedernhofer lj. Mutat Res. 2006 Apr 11;596(1-2):22-35. doi: 10.1016/j.mrfmmm.2005.11.008. Epub 2006 Feb 10. Mutat Res. 2006. PMID: 16472827

10

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

Niedernhofer LJ, Garinis GA, Raams A, Lalai AS, Robinson AR, Appeldoorn E, Odijk H, Oostendorp R, Ahmad A, van Leeuwen W, Theil AF, Vermeulen W, van der Horst GT, Meinecke P, Kleijer WJ, Vijg J, Jaspers NG, Hoeijmakers JH. Niedernhofer LJ, et al. Nature. 2006 Dec 21;444(7122):1038-43. doi: 10.1038/nature05456. Nature. 2006. PMID: 17183314

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