Thomas EA - Search Results

1

Selective histone deacetylase (HDAC) inhibition imparts beneficial effects in Huntington's disease mice: implications for the ubiquitin-proteasomal and autophagy systems.

Jia H, Kast RJ, Steffan JS, Thomas EA. Jia H, et al. Among authors: thomas ea. Hum Mol Genet. 2012 Dec 15;21(24):5280-93. doi: 10.1093/hmg/dds379. Epub 2012 Sep 10. Hum Mol Genet. 2012. PMID: 22965876 Free PMC article.

2

HDAC inhibition imparts beneficial transgenerational effects in Huntington's disease mice via altered DNA and histone methylation.

Jia H, Morris CD, Williams RM, Loring JF, Thomas EA. Jia H, et al. Among authors: thomas ea. Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):E56-64. doi: 10.1073/pnas.1415195112. Epub 2014 Dec 22. Proc Natl Acad Sci U S A. 2015. PMID: 25535382 Free PMC article.

3

The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice.

Jia H, Wang Y, Morris CD, Jacques V, Gottesfeld JM, Rusche JR, Thomas EA. Jia H, et al. Among authors: thomas ea. PLoS One. 2016 Mar 31;11(3):e0152498. doi: 10.1371/journal.pone.0152498. eCollection 2016. PLoS One. 2016. PMID: 27031333 Free PMC article.

4

Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease.

Jia H, Pallos J, Jacques V, Lau A, Tang B, Cooper A, Syed A, Purcell J, Chen Y, Sharma S, Sangrey GR, Darnell SB, Plasterer H, Sadri-Vakili G, Gottesfeld JM, Thompson LM, Rusche JR, Marsh JL, Thomas EA. Jia H, et al. Among authors: thomas ea. Neurobiol Dis. 2012 May;46(2):351-61. doi: 10.1016/j.nbd.2012.01.016. Neurobiol Dis. 2012. PMID: 22590724 Free PMC article.

5

Epigenetic changes at gene promoters in response to immune activation in utero.

Tang B, Jia H, Kast RJ, Thomas EA. Tang B, et al. Among authors: thomas ea. Brain Behav Immun. 2013 May;30:168-75. doi: 10.1016/j.bbi.2013.01.086. Epub 2013 Feb 9. Brain Behav Immun. 2013. PMID: 23402795

6

Disease Modifying Potential of Glatiramer Acetate in Huntington's Disease.

Corey-Bloom J, Jia H, Aikin AM, Thomas EA. Corey-Bloom J, et al. Among authors: thomas ea. J Huntingtons Dis. 2014;3(3):311-6. doi: 10.3233/JHD-140110. J Huntingtons Dis. 2014. PMID: 25300334 Free PMC article.

7

In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons.

Thomas EA, Coppola G, Tang B, Kuhn A, Kim S, Geschwind DH, Brown TB, Luthi-Carter R, Ehrlich ME. Thomas EA, et al. Hum Mol Genet. 2011 Mar 15;20(6):1049-60. doi: 10.1093/hmg/ddq548. Epub 2010 Dec 20. Hum Mol Genet. 2011. PMID: 21177255 Free PMC article.

8

Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease.

Tang B, Becanovic K, Desplats PA, Spencer B, Hill AM, Connolly C, Masliah E, Leavitt BR, Thomas EA. Tang B, et al. Among authors: thomas ea. Hum Mol Genet. 2012 Jul 15;21(14):3097-111. doi: 10.1093/hmg/dds132. Epub 2012 Apr 6. Hum Mol Genet. 2012. PMID: 22492998 Free PMC article.

9

Focal nature of neurological disorders necessitates isotype-selective histone deacetylase (HDAC) inhibitors.

Thomas EA. Thomas EA. Mol Neurobiol. 2009 Aug;40(1):33-45. doi: 10.1007/s12035-009-8067-y. Epub 2009 Apr 28. Mol Neurobiol. 2009. PMID: 19396637 Review.

10

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.

Thomas EA, Coppola G, Desplats PA, Tang B, Soragni E, Burnett R, Gao F, Fitzgerald KM, Borok JF, Herman D, Geschwind DH, Gottesfeld JM. Thomas EA, et al. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15564-9. doi: 10.1073/pnas.0804249105. Epub 2008 Sep 30. Proc Natl Acad Sci U S A. 2008. PMID: 18829438 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

264 results

Search Page

Filters