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Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B.
Rao S, Lee SY, Gutierrez A, Perrigoue J, Thapa RJ, Tu Z, Jeffers JR, Rhodes M, Anderson S, Oravecz T, Hunger SP, Timakhov RA, Zhang R, Balachandran S, Zambetti GP, Testa JR, Look AT, Wiest DL. Rao S, et al. Among authors: look at. Blood. 2012 Nov 1;120(18):3764-73. doi: 10.1182/blood-2012-03-415349. Epub 2012 Sep 13. Blood. 2012. PMID: 22976955 Free PMC article.
Inactivation of LEF1 in T-cell acute lymphoblastic leukemia.
Gutierrez A, Sanda T, Ma W, Zhang J, Grebliunaite R, Dahlberg S, Neuberg D, Protopopov A, Winter SS, Larson RS, Borowitz MJ, Silverman LB, Chin L, Hunger SP, Jamieson C, Sallan SE, Look AT. Gutierrez A, et al. Among authors: look at. Blood. 2010 Apr 8;115(14):2845-51. doi: 10.1182/blood-2009-07-234377. Epub 2010 Feb 1. Blood. 2010. PMID: 20124220 Free PMC article.
The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia.
Gutierrez A, Kentsis A, Sanda T, Holmfeldt L, Chen SC, Zhang J, Protopopov A, Chin L, Dahlberg SE, Neuberg DS, Silverman LB, Winter SS, Hunger SP, Sallan SE, Zha S, Alt FW, Downing JR, Mullighan CG, Look AT. Gutierrez A, et al. Among authors: look at. Blood. 2011 Oct 13;118(15):4169-73. doi: 10.1182/blood-2010-11-318873. Epub 2011 Aug 30. Blood. 2011. PMID: 21878675 Free PMC article. Clinical Trial.
High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia.
Gutierrez A, Sanda T, Grebliunaite R, Carracedo A, Salmena L, Ahn Y, Dahlberg S, Neuberg D, Moreau LA, Winter SS, Larson R, Zhang J, Protopopov A, Chin L, Pandolfi PP, Silverman LB, Hunger SP, Sallan SE, Look AT. Gutierrez A, et al. Among authors: look at. Blood. 2009 Jul 16;114(3):647-50. doi: 10.1182/blood-2009-02-206722. Epub 2009 May 20. Blood. 2009. PMID: 19458356 Free PMC article.
NOTCH and PI3K-AKT pathways intertwined.
Gutierrez A, Look AT. Gutierrez A, et al. Among authors: look at. Cancer Cell. 2007 Nov;12(5):411-3. doi: 10.1016/j.ccr.2007.10.027. Cancer Cell. 2007. PMID: 17996644 Free article.
Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia.
Gutierrez A, Grebliunaite R, Feng H, Kozakewich E, Zhu S, Guo F, Payne E, Mansour M, Dahlberg SE, Neuberg DS, den Hertog J, Prochownik EV, Testa JR, Harris M, Kanki JP, Look AT. Gutierrez A, et al. Among authors: look at. J Exp Med. 2011 Aug 1;208(8):1595-603. doi: 10.1084/jem.20101691. Epub 2011 Jul 4. J Exp Med. 2011. PMID: 21727187 Free PMC article.
440 results