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Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension.
Sharma S, Sud N, Wiseman DA, Carter AL, Kumar S, Hou Y, Rau T, Wilham J, Harmon C, Oishi P, Fineman JR, Black SM. Sharma S, et al. Among authors: hou y. Am J Physiol Lung Cell Mol Physiol. 2008 Jan;294(1):L46-56. doi: 10.1152/ajplung.00247.2007. Epub 2007 Nov 16. Am J Physiol Lung Cell Mol Physiol. 2008. PMID: 18024721 Free PMC article.
Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase.
Sun X, Kumar S, Sharma S, Aggarwal S, Lu Q, Gross C, Rafikova O, Lee SG, Dasarathy S, Hou Y, Meadows ML, Han W, Su Y, Fineman JR, Black SM. Sun X, et al. Among authors: hou y. Am J Respir Cell Mol Biol. 2014 Jun;50(6):1084-95. doi: 10.1165/rcmb.2013-0187OC. Am J Respir Cell Mol Biol. 2014. PMID: 24392990 Free PMC article.
Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury.
Kumar S, Sun X, Noonepalle SK, Lu Q, Zemskov E, Wang T, Aggarwal S, Gross C, Sharma S, Desai AA, Hou Y, Dasarathy S, Qu N, Reddy V, Lee SG, Cherian-Shaw M, Yuan JX, Catravas JD, Rafikov R, Garcia JGN, Black SM. Kumar S, et al. Among authors: hou y. Free Radic Biol Med. 2017 Jan;102:217-228. doi: 10.1016/j.freeradbiomed.2016.11.008. Epub 2016 Nov 9. Free Radic Biol Med. 2017. PMID: 27838434 Free PMC article.
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