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A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone.
Grzegorzewicz AE, Korduláková J, Jones V, Born SE, Belardinelli JM, Vaquié A, Gundi VA, Madacki J, Slama N, Laval F, Vaubourgeix J, Crew RM, Gicquel B, Daffé M, Morbidoni HR, Brennan PJ, Quémard A, McNeil MR, Jackson M. Grzegorzewicz AE, et al. Among authors: belardinelli jm. J Biol Chem. 2012 Nov 9;287(46):38434-41. doi: 10.1074/jbc.M112.400994. Epub 2012 Sep 21. J Biol Chem. 2012. PMID: 23002234 Free PMC article.
IQG-607 abrogates the synthesis of mycolic acids and displays intracellular activity against Mycobacterium tuberculosis in infected macrophages.
Rodrigues-Junior VS, dos Santos Junior AA, Villela AD, Belardinelli JM, Morbidoni HR, Basso LA, Campos MM, Santos DS. Rodrigues-Junior VS, et al. Among authors: belardinelli jm. Int J Antimicrob Agents. 2014 Jan;43(1):82-5. doi: 10.1016/j.ijantimicag.2013.08.021. Epub 2013 Oct 1. Int J Antimicrob Agents. 2014. PMID: 24139881
The cell envelope glycoconjugates of Mycobacterium tuberculosis.
Angala SK, Belardinelli JM, Huc-Claustre E, Wheat WH, Jackson M. Angala SK, et al. Among authors: belardinelli jm. Crit Rev Biochem Mol Biol. 2014 Sep-Oct;49(5):361-99. doi: 10.3109/10409238.2014.925420. Epub 2014 Jun 10. Crit Rev Biochem Mol Biol. 2014. PMID: 24915502 Free PMC article. Review.
Assembling of the Mycobacterium tuberculosis Cell Wall Core.
Grzegorzewicz AE, de Sousa-d'Auria C, McNeil MR, Huc-Claustre E, Jones V, Petit C, Angala SK, Zemanová J, Wang Q, Belardinelli JM, Gao Q, Ishizaki Y, Mikušová K, Brennan PJ, Ronning DR, Chami M, Houssin C, Jackson M. Grzegorzewicz AE, et al. Among authors: belardinelli jm. J Biol Chem. 2016 Sep 2;291(36):18867-79. doi: 10.1074/jbc.M116.739227. Epub 2016 Jul 14. J Biol Chem. 2016. PMID: 27417139 Free PMC article.
34 results