Morris ME - Search Results

1

Mechanism-based pharmacodynamic modeling.

Felmlee MA, Morris ME, Mager DE. Felmlee MA, et al. Among authors: morris me. Methods Mol Biol. 2012;929:583-600. doi: 10.1007/978-1-62703-050-2_21. Methods Mol Biol. 2012. PMID: 23007443 Free PMC article.

2

Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid.

Morris ME, Felmlee MA. Morris ME, et al. AAPS J. 2008 Jun;10(2):311-21. doi: 10.1208/s12248-008-9035-6. Epub 2008 Jun 4. AAPS J. 2008. PMID: 18523892 Free PMC article. Review.

3

Monocarboxylate transporter-mediated transport of gamma-hydroxybutyric acid in human intestinal Caco-2 cells.

Lam WK, Felmlee MA, Morris ME. Lam WK, et al. Among authors: morris me. Drug Metab Dispos. 2010 Mar;38(3):441-7. doi: 10.1124/dmd.109.030775. Epub 2009 Dec 1. Drug Metab Dispos. 2010. PMID: 19952290 Free PMC article.

4

Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid.

Felmlee MA, Roiko SA, Morse BL, Morris ME. Felmlee MA, et al. Among authors: morris me. J Pharmacol Exp Ther. 2010 Jun;333(3):764-71. doi: 10.1124/jpet.109.165381. Epub 2010 Mar 9. J Pharmacol Exp Ther. 2010. PMID: 20215411 Free PMC article.

5

Mechanistic toxicokinetic model for gamma-hydroxybutyric acid: inhibition of active renal reabsorption as a potential therapeutic strategy.

Felmlee MA, Wang Q, Cui D, Roiko SA, Morris ME. Felmlee MA, et al. Among authors: morris me. AAPS J. 2010 Sep;12(3):407-16. doi: 10.1208/s12248-010-9197-x. Epub 2010 May 12. AAPS J. 2010. PMID: 20461486 Free PMC article.

6

Use of a local sensitivity analysis to inform study design based on a mechanistic toxicokinetic model for γ-hydroxybutyric acid.

Felmlee MA, Krzyzanski W, Morse BL, Morris ME. Felmlee MA, et al. Among authors: morris me. AAPS J. 2011 Jun;13(2):240-54. doi: 10.1208/s12248-011-9264-y. Epub 2011 Mar 9. AAPS J. 2011. PMID: 21387146 Free PMC article.

7

γ-Hydroxybutyrate blood/plasma partitioning: effect of physiologic pH on transport by monocarboxylate transporters.

Morse BL, Felmlee MA, Morris ME. Morse BL, et al. Among authors: morris me. Drug Metab Dispos. 2012 Jan;40(1):64-9. doi: 10.1124/dmd.111.041285. Epub 2011 Oct 5. Drug Metab Dispos. 2012. PMID: 21976619 Free PMC article.

8

Brain uptake of the drug of abuse γ-hydroxybutyric acid in rats.

Roiko SA, Felmlee MA, Morris ME. Roiko SA, et al. Among authors: morris me. Drug Metab Dispos. 2012 Jan;40(1):212-8. doi: 10.1124/dmd.111.041749. Epub 2011 Oct 21. Drug Metab Dispos. 2012. PMID: 22019629 Free PMC article.

9

Mechanistic models describing active renal reabsorption and secretion: a simulation-based study.

Felmlee MA, Dave RA, Morris ME. Felmlee MA, et al. Among authors: morris me. AAPS J. 2013 Jan;15(1):278-87. doi: 10.1208/s12248-012-9437-3. Epub 2012 Nov 30. AAPS J. 2013. PMID: 23196805 Free PMC article.

10

Brain extracellular γ-hydroxybutyrate concentrations are decreased by L-lactate in rats: role in the treatment of overdoses.

Roiko SA, Vijay N, Felmlee MA, Morris ME. Roiko SA, et al. Among authors: morris me. Pharm Res. 2013 May;30(5):1338-48. doi: 10.1007/s11095-013-0973-z. Epub 2013 Jan 15. Pharm Res. 2013. PMID: 23319173 Free PMC article.

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