Cobb SR - Search Results

1

Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice.

Gadalla KK, Bailey ME, Spike RC, Ross PD, Woodard KT, Kalburgi SN, Bachaboina L, Deng JV, West AE, Samulski RJ, Gray SJ, Cobb SR. Gadalla KK, et al. Among authors: cobb sr. Mol Ther. 2013 Jan;21(1):18-30. doi: 10.1038/mt.2012.200. Epub 2012 Sep 25. Mol Ther. 2013. PMID: 23011033 Free PMC article.

2

Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits.

Gadalla KK, Ross PD, Riddell JS, Bailey ME, Cobb SR. Gadalla KK, et al. Among authors: cobb sr. PLoS One. 2014 Nov 13;9(11):e112889. doi: 10.1371/journal.pone.0112889. eCollection 2014. PLoS One. 2014. PMID: 25392929 Free PMC article.

3

Improved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery.

Sinnett SE, Hector RD, Gadalla KKE, Heindel C, Chen D, Zaric V, Bailey MES, Cobb SR, Gray SJ. Sinnett SE, et al. Among authors: cobb sr. Mol Ther Methods Clin Dev. 2017 Apr 19;5:106-115. doi: 10.1016/j.omtm.2017.04.006. eCollection 2017 Jun 16. Mol Ther Methods Clin Dev. 2017. PMID: 28497072 Free PMC article.

4

MeCP2 and Rett syndrome: reversibility and potential avenues for therapy.

Gadalla KK, Bailey ME, Cobb SR. Gadalla KK, et al. Among authors: cobb sr. Biochem J. 2011 Oct 1;439(1):1-14. doi: 10.1042/BJ20110648. Biochem J. 2011. PMID: 21916843 Review.

5

Rett syndrome: from bed to bench.

Weng SM, Bailey ME, Cobb SR. Weng SM, et al. Among authors: cobb sr. Pediatr Neonatol. 2011 Dec;52(6):309-16. doi: 10.1016/j.pedneo.2011.08.002. Epub 2011 Nov 6. Pediatr Neonatol. 2011. PMID: 22192257 Free article. Review.

6

Synaptic plasticity deficits in an experimental model of rett syndrome: long-term potentiation saturation and its pharmacological reversal.

Weng SM, McLeod F, Bailey ME, Cobb SR. Weng SM, et al. Among authors: cobb sr. Neuroscience. 2011 Apr 28;180:314-21. doi: 10.1016/j.neuroscience.2011.01.061. Epub 2011 Feb 4. Neuroscience. 2011. PMID: 21296130

7

Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes.

Ross PD, Guy J, Selfridge J, Kamal B, Bahey N, Tanner KE, Gillingwater TH, Jones RA, Loughrey CM, McCarroll CS, Bailey ME, Bird A, Cobb S. Ross PD, et al. Hum Mol Genet. 2016 Oct 15;25(20):4389-4404. doi: 10.1093/hmg/ddw269. Hum Mol Genet. 2016. PMID: 28173151 Free PMC article.

8

Characterisation of Cdkl5 transcript isoforms in rat.

Hector RD, Dando O, Ritakari TE, Kind PC, Bailey ME, Cobb SR. Hector RD, et al. Among authors: cobb sr. Gene. 2017 Mar 1;603:21-26. doi: 10.1016/j.gene.2016.12.001. Epub 2016 Dec 7. Gene. 2017. PMID: 27940108 Free article.

9

Development of a Novel AAV Gene Therapy Cassette with Improved Safety Features and Efficacy in a Mouse Model of Rett Syndrome.

Gadalla KKE, Vudhironarit T, Hector RD, Sinnett S, Bahey NG, Bailey MES, Gray SJ, Cobb SR. Gadalla KKE, et al. Among authors: cobb sr. Mol Ther Methods Clin Dev. 2017 Apr 22;5:180-190. doi: 10.1016/j.omtm.2017.04.007. eCollection 2017 Jun 16. Mol Ther Methods Clin Dev. 2017. PMID: 28497075 Free PMC article.

10

Reduced axonal diameter of peripheral nerve fibers in a mouse model of Rett syndrome.

Bahey NG, Gadalla KKE, McGonigal R, Bailey MES, Edgar JM, Cobb SR. Bahey NG, et al. Among authors: cobb sr. Neuroscience. 2017 Sep 1;358:261-268. doi: 10.1016/j.neuroscience.2017.06.061. Epub 2017 Jul 4. Neuroscience. 2017. PMID: 28687309

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