Spooner E - Search Results

1

Inhibiting aurora kinases reduces tumor growth and suppresses tumor recurrence after chemotherapy in patient-derived triple-negative breast cancer xenografts.

Romanelli A, Clark A, Assayag F, Chateau-Joubert S, Poupon MF, Servely JL, Fontaine JJ, Liu X, Spooner E, Goodstal S, de Cremoux P, Bièche I, Decaudin D, Marangoni E. Romanelli A, et al. Among authors: spooner e. Mol Cancer Ther. 2012 Dec;11(12):2693-703. doi: 10.1158/1535-7163.MCT-12-0441-T. Epub 2012 Sep 25. Mol Cancer Ther. 2012. PMID: 23012245

2

A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit.

Kopinja J, Sevilla RS, Levitan D, Dai D, Vanko A, Spooner E, Ware C, Forget R, Hu K, Kral A, Spacciapoli P, Kennan R, Jayaraman L, Pucci V, Perera S, Zhang W, Fischer C, Lam MH. Kopinja J, et al. Among authors: spooner e. Sci Rep. 2017 Oct 23;7(1):13853. doi: 10.1038/s41598-017-14065-w. Sci Rep. 2017. PMID: 29062039 Free PMC article.

3

Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.

Chang W, Altman MD, Lesburg CA, Perera SA, Piesvaux JA, Schroeder GK, Wyss DF, Cemerski S, Chen Y, DiNunzio E, Haidle AM, Ho T, Kariv I, Knemeyer I, Kopinja JE, Lacey BM, Laskey J, Lim J, Long BJ, Ma Y, Maddess ML, Pan BS, Presland JP, Spooner E, Steinhuebel D, Truong Q, Zhang Z, Fu J, Addona GH, Northrup AB, Parmee E, Tata JR, Bennett DJ, Cumming JN, Siu T, Trotter BW. Chang W, et al. Among authors: spooner e. J Med Chem. 2022 Apr 14;65(7):5675-5689. doi: 10.1021/acs.jmedchem.1c02197. Epub 2022 Mar 25. J Med Chem. 2022. PMID: 35332774

4

Dendrimeric Abeta1-15 is an effective immunogen in wildtype and APP-tg mice.

Seabrook TJ, Thomas K, Jiang L, Bloom J, Spooner E, Maier M, Bitan G, Lemere CA. Seabrook TJ, et al. Among authors: spooner e. Neurobiol Aging. 2007 Jun;28(6):813-23. doi: 10.1016/j.neurobiolaging.2006.04.007. Epub 2006 May 24. Neurobiol Aging. 2007. PMID: 16725229

5

Intranasal immunotherapy for the treatment of Alzheimer's disease: Escherichia coli LT and LT(R192G) as mucosal adjuvants.

Lemere CA, Spooner ET, Leverone JF, Mori C, Clements JD. Lemere CA, et al. Neurobiol Aging. 2002 Nov-Dec;23(6):991-1000. doi: 10.1016/s0197-4580(02)00127-6. Neurobiol Aging. 2002. PMID: 12470794

6

Abeta1-15 is less immunogenic than Abeta1-40/42 for intranasal immunization of wild-type mice but may be effective for "boosting".

Leverone JF, Spooner ET, Lehman HK, Clements JD, Lemere CA. Leverone JF, et al. Vaccine. 2003 May 16;21(17-18):2197-206. doi: 10.1016/s0264-410x(02)00754-5. Vaccine. 2003. PMID: 12706711

7

Amyloid-beta immunization in Alzheimer's disease transgenic mouse models and wildtype mice.

Lemere CA, Spooner ET, Leverone JF, Mori C, Iglesias M, Bloom JK, Seabrook TJ. Lemere CA, et al. Neurochem Res. 2003 Jul;28(7):1017-27. doi: 10.1023/a:1023203122036. Neurochem Res. 2003. PMID: 12737526 Review.

8

Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice.

Lemere CA, Spooner ET, LaFrancois J, Malester B, Mori C, Leverone JF, Matsuoka Y, Taylor JW, DeMattos RB, Holtzman DM, Clements JD, Selkoe DJ, Duff KE. Lemere CA, et al. Among authors: spooner et. Neurobiol Dis. 2003 Oct;14(1):10-8. doi: 10.1016/s0969-9961(03)00044-5. Neurobiol Dis. 2003. PMID: 13678662

9

Alzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet.

Lemere CA, Beierschmitt A, Iglesias M, Spooner ET, Bloom JK, Leverone JF, Zheng JB, Seabrook TJ, Louard D, Li D, Selkoe DJ, Palmour RM, Ervin FR. Lemere CA, et al. Am J Pathol. 2004 Jul;165(1):283-97. doi: 10.1016/s0002-9440(10)63296-8. Am J Pathol. 2004. PMID: 15215183 Free PMC article.

10

Species-specific immune response to immunization with human versus rodent A beta peptide.

Seabrook TJ, Bloom JK, Iglesias M, Spooner ET, Walsh DM, Lemere CA. Seabrook TJ, et al. Neurobiol Aging. 2004 Oct;25(9):1141-51. doi: 10.1016/j.neurobiolaging.2003.12.008. Neurobiol Aging. 2004. PMID: 15312960

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